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Molidustat (INN; Bay 85-3934) is a drug which acts as an HIF prolyl-hydroxylase inhibitor and thereby increases endogenous production of erythropoietin, which stimulates production of hemoglobin and red blood cells. It is in Phase III clinical trials for the treatment of anemia caused by chronic kidney disease. Due to its potential applications in athletic doping, it has also been incorporated into screens for performance-enhancing drugs.

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rdfs:label
  • Molidustat (de)
  • Molidustat (en)
rdfs:comment
  • Molidustat ist ein , der die Produktion von Hämoglobin und Erythrozyten stimuliert. Es wurde im Januar 2021 in Japan unter dem Namen Musredo (Bayer Yakuhin) zugelassen zur oralen Behandlung der Anämie („Blutarmut“) infolge einer chronischen Nierenerkrankung (CDK). (de)
  • Molidustat (INN; Bay 85-3934) is a drug which acts as an HIF prolyl-hydroxylase inhibitor and thereby increases endogenous production of erythropoietin, which stimulates production of hemoglobin and red blood cells. It is in Phase III clinical trials for the treatment of anemia caused by chronic kidney disease. Due to its potential applications in athletic doping, it has also been incorporated into screens for performance-enhancing drugs. (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Molidustat_structure.png
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ATC prefix
  • None (en)
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CAS number
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IUPAC name
KEGG
  • D12122 (en)
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PubChem
SMILES
  • C1COCCN1C2=NC=NCN3CCN4C=CN=N4 (en)
StdInChI
StdInChIKey
  • IJMBOKOTALXLKS-UHFFFAOYSA-N (en)
synonyms
  • Bay 85-3934 (en)
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has abstract
  • Molidustat ist ein , der die Produktion von Hämoglobin und Erythrozyten stimuliert. Es wurde im Januar 2021 in Japan unter dem Namen Musredo (Bayer Yakuhin) zugelassen zur oralen Behandlung der Anämie („Blutarmut“) infolge einer chronischen Nierenerkrankung (CDK). (de)
  • Molidustat (INN; Bay 85-3934) is a drug which acts as an HIF prolyl-hydroxylase inhibitor and thereby increases endogenous production of erythropoietin, which stimulates production of hemoglobin and red blood cells. It is in Phase III clinical trials for the treatment of anemia caused by chronic kidney disease. Due to its potential applications in athletic doping, it has also been incorporated into screens for performance-enhancing drugs. (en)
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page length (characters) of wiki page
CAS number
  • 1154028-82-6
FDA UNII code
  • 9JH486CZ13
KEGG
  • D12122
PubChem
  • 59603622
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