About: Molidustat

Property	Value
dbo:abstract	Molidustat ist ein , der die Produktion von Hämoglobin und Erythrozyten stimuliert. Es wurde im Januar 2021 in Japan unter dem Namen Musredo (Bayer Yakuhin) zugelassen zur oralen Behandlung der Anämie („Blutarmut“) infolge einer chronischen Nierenerkrankung (CDK). (de) Molidustat (INN; Bay 85-3934) is a drug which acts as an HIF prolyl-hydroxylase inhibitor and thereby increases endogenous production of erythropoietin, which stimulates production of hemoglobin and red blood cells. It is in Phase III clinical trials for the treatment of anemia caused by chronic kidney disease. Due to its potential applications in athletic doping, it has also been incorporated into screens for performance-enhancing drugs. (en)
dbo:casNumber	1154028-82-6
dbo:fdaUniiCode	9JH486CZ13
dbo:kegg	D12122
dbo:pubchem	59603622
dbo:thumbnail	wiki-commons:Special:FilePath/Molidustat_structure.png?width=300
dbo:wikiPageID	55985962 (xsd:integer)
dbo:wikiPageLength	3026 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1115231097 (xsd:integer)
dbo:wikiPageWikiLink	dbc:Pyrazolones dbr:Desidustat dbc:Triazoles dbr:Anemia dbr:Performance-enhancing_drugs dbr:HIF_prolyl-hydroxylase_inhibitor dbr:Daprodustat dbr:Erythropoietin dbr:Chronic_kidney_disease dbr:Red_blood_cell dbc:Morpholines dbc:Pyrimidines dbr:Hemoglobin dbr:Roxadustat dbr:Vadadustat dbr:Athletic_doping
dbp:atcPrefix	None (en)
dbp:c	13 (xsd:integer)
dbp:casNumber	1154028 (xsd:integer)
dbp:h	14 (xsd:integer)
dbp:iupacName	2 (xsd:integer)
dbp:kegg	D12122 (en)
dbp:n	8 (xsd:integer)
dbp:o	2 (xsd:integer)
dbp:pubchem	59603622 (xsd:integer)
dbp:smiles	C1COCCN1C2=NC=NCN3CCN4C=CN=N4 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	IJMBOKOTALXLKS-UHFFFAOYSA-N (en)
dbp:synonyms	Bay 85-3934 (en)
dbp:unii	9 (xsd:integer)
dbp:width	250 (xsd:integer)
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dcterms:subject	dbc:Pyrazolones dbc:Triazoles dbc:Morpholines dbc:Pyrimidines
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug
rdfs:comment	Molidustat ist ein , der die Produktion von Hämoglobin und Erythrozyten stimuliert. Es wurde im Januar 2021 in Japan unter dem Namen Musredo (Bayer Yakuhin) zugelassen zur oralen Behandlung der Anämie („Blutarmut“) infolge einer chronischen Nierenerkrankung (CDK). (de) Molidustat (INN; Bay 85-3934) is a drug which acts as an HIF prolyl-hydroxylase inhibitor and thereby increases endogenous production of erythropoietin, which stimulates production of hemoglobin and red blood cells. It is in Phase III clinical trials for the treatment of anemia caused by chronic kidney disease. Due to its potential applications in athletic doping, it has also been incorporated into screens for performance-enhancing drugs. (en)
rdfs:label	Molidustat (de) Molidustat (en)
owl:sameAs	wikidata:Molidustat dbpedia-de:Molidustat https://global.dbpedia.org/id/2XsXc
prov:wasDerivedFrom	wikipedia-en:Molidustat?oldid=1115231097&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Molidustat_structure.png
foaf:isPrimaryTopicOf	wikipedia-en:Molidustat
is dbo:wikiPageRedirects of	dbr:Molidustat_sodium
is dbo:wikiPageWikiLink of	dbr:List_of_doping_cases_in_cycling dbr:Hypoxia-inducible_factor dbr:Matija_Kvasina dbr:HIF_prolyl-hydroxylase_inhibitor dbr:Daprodustat dbr:Team_Felbermayr–Simplon_Wels dbr:Vadadustat dbr:Molidustat_sodium
is foaf:primaryTopic of	wikipedia-en:Molidustat