Egypt–Mesopotamia relations were the relations between the civilisations of ancient Egypt and Mesopotamia, in the Middle East. They seem to have developed from the 4th millennium BCE, starting in the Uruk period for Mesopotamia (circa 4000–3100 BCE) and the half a millennium younger Gerzean culture of Prehistoric Egypt (circa 3500–3200 BCE), and constituted a largely one way body of influences from Mesopotamia into Egypt.