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In genetics, underdominance, also known as homozygote advantage, heterozygote disadvantage, or negative overdominance," is the opposite of overdominance. It is the selection against the heterozygote, causing disruptive selection and divergent genotypes. Underdominance exists in situations where the heterozygotic genotype is inferior in fitness to either the dominant or recessive homozygotic genotype. Compared to examples of overdominance in actual populations, underdominance is considered more unstable and may lead to the fixation of either allele.

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rdfs:label	Underdominance (en)
rdfs:comment	In genetics, underdominance, also known as homozygote advantage, heterozygote disadvantage, or negative overdominance," is the opposite of overdominance. It is the selection against the heterozygote, causing disruptive selection and divergent genotypes. Underdominance exists in situations where the heterozygotic genotype is inferior in fitness to either the dominant or recessive homozygotic genotype. Compared to examples of overdominance in actual populations, underdominance is considered more unstable and may lead to the fixation of either allele. (en)
dcterms:subject	Classical genetics
Wikipage page ID	1920371 (xsd:integer)
Wikipage revision ID	1100917446 (xsd:integer)
Link from a Wikipage to another Wikipage	Pseudacraea eurytus Dengue fever Allele Predation Gene knockdown Genetic equilibrium Genetics Genotype Natural selection Zygosity Mimicry Malaria Population genetics Disruptive selection Drosophila melanogaster Fixation (population genetics) Classical genetics Ecological niche Heterozygote advantage Homologous chromosome dbr:C-reactive_protein Selection Wild type Fitness (biology) Overdominance
Link from a Wikipage to an external page	https://www.jstor.org/stable/2458786%3Fseq=1%23page_scan_tab_contents https://www.researchgate.net/publication/239730600_Underdominance https://plato.stanford.edu/entries/population-genetics/ http://scholarworks.umt.edu/cgi/viewcontent.cgi%3Farticle=5417&context=etd http://www.biology.arizona.edu/biomath/tutorials/polynomial/Applications/Underdominance.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1461441/
sameAs	Underdominance Underdominance Underdominance
dbp:wikiPageUsesTemplate	dbt:Short_description
has abstract	In genetics, underdominance, also known as homozygote advantage, heterozygote disadvantage, or negative overdominance," is the opposite of overdominance. It is the selection against the heterozygote, causing disruptive selection and divergent genotypes. Underdominance exists in situations where the heterozygotic genotype is inferior in fitness to either the dominant or recessive homozygotic genotype. Compared to examples of overdominance in actual populations, underdominance is considered more unstable and may lead to the fixation of either allele. An example of stable underdominance may occur in individuals who are heterozygotic for polymorphisms that would make them better suited for one of two niches. Consider a situation in which a population is completely homozygotic for an "A" allele, allowing exploitation of a particular resource. Eventually, a polymorphic "a" allele may be introduced into the population, resulting in an individual who is capable of exploiting a different resource. This would result in an "aa" homozygotic invasion of the population due to nonexistent competition of the unexploited resource. The frequency of "aa" individuals would increase until the abundance of the "a" resource begins to decline. Eventually, the "AA" and "aa" genotypes would reach equilibrium with each other, with "Aa" heterozygotic individuals potentially experiencing a reduced fitness compared to those individuals who are homozygotic for utilization of either resource. This example of underdominance is stable because any shift in equilibrium would result in selection for the rare allele due to increased resource abundance. This compensatory selection would ultimately return the dimorphic system to underdominant equilibrium. (en)
gold:hypernym	Opposite
prov:wasDerivedFrom	wikipedia-en:Underdominance?oldid=1100917446&ns=0
page length (characters) of wiki page	8112 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Underdominance
is Link from a Wikipage to another Wikipage of	Pseudacraea eurytus Index of genetics articles Cline (biology) Glossary of genetics Glossary of genetics (M−Z) Population genetics Disruptive selection Balancing selection Reinforcement (speciation) Heredity Heterozygote advantage Overdominance Parapatric speciation
is foaf:primaryTopic of	wikipedia-en:Underdominance

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