About: Uprifosbuvir

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Uprifosbuvir (MK-3682) is an antiviral drug developed for the treatment of Hepatitis C. It is a nucleotide analogue which acts as an NS5B RNA polymerase inhibitor. It is currently in Phase III human clinical trials.

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dbo:abstract
  • Uprifosbuvir (MK-3682) is an antiviral drug developed for the treatment of Hepatitis C. It is a nucleotide analogue which acts as an NS5B RNA polymerase inhibitor. It is currently in Phase III human clinical trials. (en)
  • 乌普立布韦(英语:Uprifosbuvir,MK-3682)是一种开发用于治疗丙型肝炎的抗病毒药物。它是一种核苷酸类似物,可用作 RNA聚合酶抑制剂,目前处于III期人体临床试验中。 (zh)
dbo:alternativeName
  • Uprifosbuvir (en)
dbo:casNumber
  • 1496551-77-9
dbo:chEMBL
  • 3833371
dbo:drugbank
  • DB15206
dbo:fdaUniiCode
  • JW31KPS26S
dbo:kegg
  • D10996
dbo:pubchem
  • 90055716
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  • 22 (xsd:integer)
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  • 1496551 (xsd:integer)
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  • 3833371 (xsd:integer)
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  • 57427403 (xsd:integer)
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  • 1 (xsd:integer)
dbp:drugbank
  • DB15206 (en)
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  • 29 (xsd:integer)
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  • propan-2-yl -2-[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate (en)
dbp:kegg
  • D10996 (en)
dbp:legalUs
  • Investigational New Drug (en)
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  • 545.900000 (xsd:double)
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  • 3 (xsd:integer)
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  • 9 (xsd:integer)
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  • C[C@H]N[P@@]OC3=CC=CC=C3 (en)
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  • SFPFZQKYPOWCSI-KHFYHRBSSA-N (en)
dbp:tradename
  • Uprifosbuvir (en)
dbp:unii
  • JW31KPS26S (en)
dbp:wikiPageUsesTemplate
dcterms:subject
rdf:type
rdfs:comment
  • Uprifosbuvir (MK-3682) is an antiviral drug developed for the treatment of Hepatitis C. It is a nucleotide analogue which acts as an NS5B RNA polymerase inhibitor. It is currently in Phase III human clinical trials. (en)
  • 乌普立布韦(英语:Uprifosbuvir,MK-3682)是一种开发用于治疗丙型肝炎的抗病毒药物。它是一种核苷酸类似物,可用作 RNA聚合酶抑制剂,目前处于III期人体临床试验中。 (zh)
rdfs:label
  • Uprifosbuvir (en)
  • 乌普立布韦 (zh)
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foaf:depiction
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is foaf:primaryTopic of
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