An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Trichlormethiazide (INN, currently being sold under the brand names of Achletin, Diu-Hydrin and Triflumen) is a diuretic with properties similar to those of hydrochlorothiazide. It is usually administered for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension. In veterinary medicine, trichlormethiazide can be combined with dexamethasone to be used on horses with mild swelling of distal limbs and general bruising.

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dbo:abstract
  • ثلاثي كلورميثيازيد (بالإنجليزية: Trichlormethiazide)‏ هو دواء يُستعمل في علاج: * متلازمة كلوية * استسقاء عام * فشل القلب الاحتقاني * ارتفاع ضغط الدم (ar)
  • Triclormetiazida es el nombre del principio activo de un diurético antihipertensivo del grupo de las tiazidas con propiedades muy similares a las del hidroclorotiazida.​ En administración oral para tratar el edema, la politiazida se toma de 1 a 4 mg diarios y para pacientes hipertensos se suele administrar 2 a 4 mg diarios.​ (es)
  • トリクロルメチアジド(Trichlormethiazide)はヒドロクロロチアジドと同じくチアジド系降圧利尿薬の一つである。腎臓の遠位尿細管でのNa+/Cl−再吸収を阻害する。またK+の排泄を増加させる。通常、心不全、肝硬変、副腎皮質ホルモン治療、その他に伴う浮腫の治療や高血圧の治療に使用される。獣医学の分野では、ウマの四肢遠位の軽度腫脹や打撲の治療にデキサメタゾンと併用される。商品名フルイトラン、塩野義製薬製造販売。 (ja)
  • La triclormetiazide è un diuretico tiazidico con proprietà simili a quelle della idroclorotiazide. A parità di dosaggio sembra essere più efficace di altri diuretici della stessa famiglia.L'effetto diuretico si manifesta entro due ore dalla somministrazione e dura circa 24 ore. (it)
  • Trichlormethiazide (INN, currently being sold under the brand names of Achletin, Diu-Hydrin and Triflumen) is a diuretic with properties similar to those of hydrochlorothiazide. It is usually administered for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension. In veterinary medicine, trichlormethiazide can be combined with dexamethasone to be used on horses with mild swelling of distal limbs and general bruising. As a diuretic (in particular a thiazide), trichlormethiazide encourages water loss from the body. Trichlormethiazide works by inhibiting Na+/Cl− ion reabsorption from the distal tubules of the kidneys. In addition, trichlormethiazide increases the excretion of potassium. (en)
dbo:casNumber
  • 133-67-5
dbo:chEMBL
  • 1054
dbo:drugbank
  • DB01021
dbo:fdaUniiCode
  • Q58C92TUN0
dbo:kegg
  • D00658
dbo:pubchem
  • 5560
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  • 3.0
dbp:atcSuffix
  • AA03 (en)
dbp:bioavailability
  • Variably absorbed from GI tract (en)
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  • 8 (xsd:integer)
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  • 133 (xsd:integer)
dbp:chembl
  • 1054 (xsd:integer)
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  • 5359 (xsd:integer)
dbp:cl
  • 3 (xsd:integer)
dbp:drugbank
  • DB01021 (en)
dbp:excretion
  • Primarily excreted unchanged in urine (en)
dbp:h
  • 8 (xsd:integer)
dbp:image
  • Trichlormethiazide-3D-spacefill.png (en)
dbp:iupacName
  • 6 (xsd:integer)
dbp:iupharLigand
  • 7314 (xsd:integer)
dbp:kegg
  • D00658 (en)
dbp:legalStatus
  • Rx-only (en)
dbp:n
  • 3 (xsd:integer)
dbp:o
  • 4 (xsd:integer)
dbp:pregnancyCategory
  • B (en)
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  • 5560 (xsd:integer)
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  • Oral (en)
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  • 2 (xsd:integer)
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  • Q58C92TUN0 (en)
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  • changed (en)
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  • changed (en)
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dcterms:subject
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rdfs:comment
  • ثلاثي كلورميثيازيد (بالإنجليزية: Trichlormethiazide)‏ هو دواء يُستعمل في علاج: * متلازمة كلوية * استسقاء عام * فشل القلب الاحتقاني * ارتفاع ضغط الدم (ar)
  • Triclormetiazida es el nombre del principio activo de un diurético antihipertensivo del grupo de las tiazidas con propiedades muy similares a las del hidroclorotiazida.​ En administración oral para tratar el edema, la politiazida se toma de 1 a 4 mg diarios y para pacientes hipertensos se suele administrar 2 a 4 mg diarios.​ (es)
  • トリクロルメチアジド(Trichlormethiazide)はヒドロクロロチアジドと同じくチアジド系降圧利尿薬の一つである。腎臓の遠位尿細管でのNa+/Cl−再吸収を阻害する。またK+の排泄を増加させる。通常、心不全、肝硬変、副腎皮質ホルモン治療、その他に伴う浮腫の治療や高血圧の治療に使用される。獣医学の分野では、ウマの四肢遠位の軽度腫脹や打撲の治療にデキサメタゾンと併用される。商品名フルイトラン、塩野義製薬製造販売。 (ja)
  • La triclormetiazide è un diuretico tiazidico con proprietà simili a quelle della idroclorotiazide. A parità di dosaggio sembra essere più efficace di altri diuretici della stessa famiglia.L'effetto diuretico si manifesta entro due ore dalla somministrazione e dura circa 24 ore. (it)
  • Trichlormethiazide (INN, currently being sold under the brand names of Achletin, Diu-Hydrin and Triflumen) is a diuretic with properties similar to those of hydrochlorothiazide. It is usually administered for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension. In veterinary medicine, trichlormethiazide can be combined with dexamethasone to be used on horses with mild swelling of distal limbs and general bruising. (en)
rdfs:label
  • ثلاثي كلورميثيازيد (ar)
  • Triclormetiazida (es)
  • Triclormetiazide (it)
  • トリクロルメチアジド (ja)
  • Trichlormethiazide (en)
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