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- (S)-Tetrahydroberberine oxidase (EC 1.3.3.8) is an enzyme that catalyzes the final transformation in the biosynthesis of berberine, a quaternary benzylisoquinoline alkaloid of the protoberberine structural subgroup. This reaction pathway catalyzes the four-electron oxidation of (S)-tetrahydroberberine (also known as (S)-canadine) in the presence of oxygen to produce berberine and hydrogen peroxide as products. (S)-Tetrahydroberberine + 2 O2 ⇌ Berberine + 2 H2O2 This enzyme belongs to the family known as oxidoreductases, in this instance the CH-CH moiety acts as the electron donor with oxygen acting as the electron acceptor. The systematic name of this enzyme is (S)-tetrahydroberberine:oxygen oxidoreductase; but it is also known as (S)-THB oxidase, tetrahydroberberine oxidase, and decreasingly, as (S)-tetrahydroprotoberberine oxidase. (en)
- La tetraidroberberina ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (S)-tetraidroberberina + 2 O2 ⇄ berberina + 2 H2O2 L'enzima di Berberis sp. è una flavoproteina, mentre quello di non lo è. Le (R)-tetraidroberberine non vengono ossidate. (it)
- テトラヒドロベルベリンオキシダーゼ(tetrahydroberberine oxidase, (S)-THB oxidase)は、イソキノリンアルカロイド生合成酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 (S)-テトラヒドロベルベリン + 2 O2 ベルベリン + 2 H2O2 反応式の通り、この酵素の基質は(S)-と酸素、生成物はベルベリンと過酸化水素である。 組織名は(S)-tetrahydroberberine:oxygen oxidoreductaseである。 (ja)
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- tetrahydroberberine oxidase (en)
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- La tetraidroberberina ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (S)-tetraidroberberina + 2 O2 ⇄ berberina + 2 H2O2 L'enzima di Berberis sp. è una flavoproteina, mentre quello di non lo è. Le (R)-tetraidroberberine non vengono ossidate. (it)
- テトラヒドロベルベリンオキシダーゼ(tetrahydroberberine oxidase, (S)-THB oxidase)は、イソキノリンアルカロイド生合成酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 (S)-テトラヒドロベルベリン + 2 O2 ベルベリン + 2 H2O2 反応式の通り、この酵素の基質は(S)-と酸素、生成物はベルベリンと過酸化水素である。 組織名は(S)-tetrahydroberberine:oxygen oxidoreductaseである。 (ja)
- (S)-Tetrahydroberberine oxidase (EC 1.3.3.8) is an enzyme that catalyzes the final transformation in the biosynthesis of berberine, a quaternary benzylisoquinoline alkaloid of the protoberberine structural subgroup. This reaction pathway catalyzes the four-electron oxidation of (S)-tetrahydroberberine (also known as (S)-canadine) in the presence of oxygen to produce berberine and hydrogen peroxide as products. (S)-Tetrahydroberberine + 2 O2 ⇌ Berberine + 2 H2O2 (en)
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- Tetraidroberberina ossidasi (it)
- テトラヒドロベルベリンオキシダーゼ (ja)
- Tetrahydroberberine oxidase (en)
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- tetrahydroberberine oxidase (en)
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