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Systems pharmacology is the application of systems biology principles to the field of pharmacology. It seeks to understand how drugs affect the human body as a single complex biological system. Instead of considering the effect of a drug to be the result of one specific , systems pharmacology considers the effect of a drug to be the outcome of the network of interactions a drug may have. In 1992, an article on systems medicine and pharmacology was published in China. Networks of interaction may include chemical-protein, protein–protein, genetic, signalling and physiological (at cellular, tissue, organ and whole body levels). Systems pharmacology uses bioinformatics and statistics techniques to integrate and interpret these networks.

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  • Systems pharmacology is the application of systems biology principles to the field of pharmacology. It seeks to understand how drugs affect the human body as a single complex biological system. Instead of considering the effect of a drug to be the result of one specific , systems pharmacology considers the effect of a drug to be the outcome of the network of interactions a drug may have. In 1992, an article on systems medicine and pharmacology was published in China. Networks of interaction may include chemical-protein, protein–protein, genetic, signalling and physiological (at cellular, tissue, organ and whole body levels). Systems pharmacology uses bioinformatics and statistics techniques to integrate and interpret these networks. Systems pharmacology can be applied to drug safety studies as a complement to pharmacoepidemiology. (en)
  • 系統藥理學(Systems pharmacology)係將系統生物學知識應用到藥理學中而產生的一門學科。該學科旨在闡明藥物如何作用於肌體的各系統。和用一種特殊的蛋白質-藥物反應來評價一種藥物的藥效不同,系統藥理學認爲藥物通過形成相互作用網絡起效。1992年在中華人民共和國的全国中西医学术会议上,B.J Zeng發表了一篇關於系統醫學以及系統藥理學的文章。相互作用系統可能會包括藥物—蛋白質、蛋白質—蛋白質的相互作用,以及遺傳學的、信號的,以及生理學上的相互作用(在細胞、組織、器官、個體水平上)。系統藥理學使用生物信息學和統計學的手段來整合、闡釋藥物相互作用的網絡。 系統藥理學可以應用於藥物安全領域,作爲對藥物流行病學的補充。EU-ADR已成功將系統藥理學納入他們的信號實體化流程之中。 (zh)
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  • 系統藥理學(Systems pharmacology)係將系統生物學知識應用到藥理學中而產生的一門學科。該學科旨在闡明藥物如何作用於肌體的各系統。和用一種特殊的蛋白質-藥物反應來評價一種藥物的藥效不同,系統藥理學認爲藥物通過形成相互作用網絡起效。1992年在中華人民共和國的全国中西医学术会议上,B.J Zeng發表了一篇關於系統醫學以及系統藥理學的文章。相互作用系統可能會包括藥物—蛋白質、蛋白質—蛋白質的相互作用,以及遺傳學的、信號的,以及生理學上的相互作用(在細胞、組織、器官、個體水平上)。系統藥理學使用生物信息學和統計學的手段來整合、闡釋藥物相互作用的網絡。 系統藥理學可以應用於藥物安全領域,作爲對藥物流行病學的補充。EU-ADR已成功將系統藥理學納入他們的信號實體化流程之中。 (zh)
  • Systems pharmacology is the application of systems biology principles to the field of pharmacology. It seeks to understand how drugs affect the human body as a single complex biological system. Instead of considering the effect of a drug to be the result of one specific , systems pharmacology considers the effect of a drug to be the outcome of the network of interactions a drug may have. In 1992, an article on systems medicine and pharmacology was published in China. Networks of interaction may include chemical-protein, protein–protein, genetic, signalling and physiological (at cellular, tissue, organ and whole body levels). Systems pharmacology uses bioinformatics and statistics techniques to integrate and interpret these networks. (en)
rdfs:label
  • Systems pharmacology (en)
  • 系統藥理學 (zh)
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