About: Sibiricine

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Sibiricine is a bioactive isoquinoline alkaloid isolated from Corydalis crispa (Fumariaceae), which is a Bhutanese medicinal plant from the Himalayas. Using high resolution mass spectrometry, the molecular formula of sibiricine is determined to be C20H17NO6. The IUPAC name for sibiricine is 8'-hydroxy-6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-8H-cyclopenta[g][1,3]benzodioxole]-6'-one. The proton nuclear magnetic resonance (PMR) spectrum of sibiricine at 100 MHz shows that sibiricine is structurally related to ochrobirine and ochotensine. With the exception of sibiricine, 8 other alkaloids are extracted by investigating Corydalis crispa. These isoquinoline alkaloids are protopine, , , stylopine, , , , and bicuculline.

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  • Sibiricine is a bioactive isoquinoline alkaloid isolated from Corydalis crispa (Fumariaceae), which is a Bhutanese medicinal plant from the Himalayas. Using high resolution mass spectrometry, the molecular formula of sibiricine is determined to be C20H17NO6. The IUPAC name for sibiricine is 8'-hydroxy-6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-8H-cyclopenta[g][1,3]benzodioxole]-6'-one. The proton nuclear magnetic resonance (PMR) spectrum of sibiricine at 100 MHz shows that sibiricine is structurally related to ochrobirine and ochotensine. With the exception of sibiricine, 8 other alkaloids are extracted by investigating Corydalis crispa. These isoquinoline alkaloids are protopine, , , stylopine, , , , and bicuculline. (en)
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  • 8'-Hydroxy-6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-8H-cyclopenta[g][1,3]benzodioxole]-6'-one (en)
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  • Sibiricine is a bioactive isoquinoline alkaloid isolated from Corydalis crispa (Fumariaceae), which is a Bhutanese medicinal plant from the Himalayas. Using high resolution mass spectrometry, the molecular formula of sibiricine is determined to be C20H17NO6. The IUPAC name for sibiricine is 8'-hydroxy-6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-8H-cyclopenta[g][1,3]benzodioxole]-6'-one. The proton nuclear magnetic resonance (PMR) spectrum of sibiricine at 100 MHz shows that sibiricine is structurally related to ochrobirine and ochotensine. With the exception of sibiricine, 8 other alkaloids are extracted by investigating Corydalis crispa. These isoquinoline alkaloids are protopine, , , stylopine, , , , and bicuculline. (en)
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  • Sibiricine (en)
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