The John F. Seagle Building (also known as Hotel Kelley or the Dixie Hotel) is a historic building located at 408 West University Avenue in Gainesville, Florida, in the United States. Built in 1926, it was designed by noted University of Florida architect and professor Rudolph Weaver and built by G. Lloyd Preacher & Company. On August 16, 1982, it was added to the National Register of Historic Places as the Dixie Hotel, Hotel Kelley.