In genetics, rs6311 is a gene variation—a single nucleotide polymorphism (SNP)—in the human HTR2A gene that codes for the 5-HT2A receptor. 5-HT2A is a neuroreceptor, and several scientific studies have investigated the effect of the genetic variation on personality, e.g., personality traits measured with the Temperament and Character Inventoryor with a psychological task measuring impulsive behavior.The SNP has also been investigated in rheumatology studies. As of 2008, meta-analysis of research studies indicates that people with the A-allele may have slightly elevated risk of schizophrenia.
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