About: Ro 3-0419

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Ro 3-0419 is a highly toxic organophosphate acetylcholinesterase inhibitor. It is the neutral analog of Ro 3-0422. Although Ro 3-0419 is less potent than Ro 3-0422, it does not have a positively charged nitrogen atom, resulting in its ability to cross the blood brain barrier to inhibit cholinesterases in the brain. The intravenous LD50 of Ro 3-0419 is 1 mg/kg in mice.

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  • Ro 3-0419 is a highly toxic organophosphate acetylcholinesterase inhibitor. It is the neutral analog of Ro 3-0422. Although Ro 3-0419 is less potent than Ro 3-0422, it does not have a positively charged nitrogen atom, resulting in its ability to cross the blood brain barrier to inhibit cholinesterases in the brain. The intravenous LD50 of Ro 3-0419 is 1 mg/kg in mice. (en)
dbo:alternativeName
  • 3-(Diethoxyphosphinyloxy)-quinoline (en)
dbo:iupacName
  • Diethyl quinolin-3-yl phosphate (en)
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  • 1673 (xsd:nonNegativeInteger)
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  • Ro 3-0419.svg (en)
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  • Ro 3-0419 (en)
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  • 3 (xsd:integer)
dbp:pin
  • Diethyl quinolin-3-yl phosphate (en)
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  • Ro 3-0419 is a highly toxic organophosphate acetylcholinesterase inhibitor. It is the neutral analog of Ro 3-0422. Although Ro 3-0419 is less potent than Ro 3-0422, it does not have a positively charged nitrogen atom, resulting in its ability to cross the blood brain barrier to inhibit cholinesterases in the brain. The intravenous LD50 of Ro 3-0419 is 1 mg/kg in mice. (en)
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  • Ro 3-0419 (en)
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  • Ro 3-0419 (en)
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