Protective isolation or reverse isolation denotes the practices used for protecting vulnerable persons for contracting an infection. When people with weakened immune systems are exposed to organisms, it could lead to infection and serious complications. It is sometimes practiced in patients with severe burns and leukemia, or those undergoing chemotherapy. When reverse isolation is practiced in or high-efficiency particulate air (HEPA)-filtered rooms, there was an improvement in survival for patients receiving bone marrow or stem cell grafts.
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