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In enzymology, a peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) is an enzyme that catalyzes a chemical reaction that cleaves a N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. This enzyme belongs to the family of hydrolases, specifically those acting on carbon-nitrogen bonds other than peptide bonds in linear amides. The NGLY1 gene encodes the ortholog of this enzyme in humans.

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dbo:abstract
  • In enzymology, a peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) is an enzyme that catalyzes a chemical reaction that cleaves a N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. This enzyme belongs to the family of hydrolases, specifically those acting on carbon-nitrogen bonds other than peptide bonds in linear amides. The NGLY1 gene encodes the ortholog of this enzyme in humans. (en)
dbo:ecNumber
  • 3.5.1.52
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  • 14503391 (xsd:integer)
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  • 4464 (xsd:nonNegativeInteger)
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  • 1058017765 (xsd:integer)
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  • Rendering based on (en)
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  • 83534 (xsd:integer)
dbp:date
  • March 2016 (en)
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  • PNGase F (en)
dbp:ecNumber
  • 3.500000 (xsd:double)
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  • 224 (xsd:integer)
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  • 3 (xsd:integer)
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  • peptide-N4-asparagine amidase (en)
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  • In enzymology, a peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) is an enzyme that catalyzes a chemical reaction that cleaves a N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. This enzyme belongs to the family of hydrolases, specifically those acting on carbon-nitrogen bonds other than peptide bonds in linear amides. The NGLY1 gene encodes the ortholog of this enzyme in humans. (en)
rdfs:label
  • Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase (en)
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  • peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase (en)
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