About: OPPPP

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

OPPPP (1-(3-Oxo-3-phenylpropyl)-4-phenyl-4-piperidinyl propionate) is an opioid drug related to medicines such as prodine. It is one of several compounds derived from MPPP, the reverse ester of pethidine, which were sold as designer drugs in the 1980s, but have been rarely encountered by law enforcement since the passage of the Federal Analogue Act in 1986. In animal studies it was found to be around 1000x the potency of pethidine, making it several times the potency of fentanyl and with similar hazards of respiratory depression and overdose. It is closely related to numerous compounds made by Janssen et al. for which the structure-activity relationship is well established.

Property	Value
dbo:abstract	OPPPP (1-(3-Oxo-3-phenylpropyl)-4-phenyl-4-piperidinyl propionate) is an opioid drug related to medicines such as prodine. It is one of several compounds derived from MPPP, the reverse ester of pethidine, which were sold as designer drugs in the 1980s, but have been rarely encountered by law enforcement since the passage of the Federal Analogue Act in 1986. In animal studies it was found to be around 1000x the potency of pethidine, making it several times the potency of fentanyl and with similar hazards of respiratory depression and overdose. It is closely related to numerous compounds made by Janssen et al. for which the structure-activity relationship is well established. (en)
dbo:casNumber	(HCl) 802832-29-7
dbo:pubchem	424788
dbo:thumbnail	wiki-commons:Special:FilePath/OPPPP_Structure.svg?width=300
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dbo:wikiPageWikiLink	dbr:Prodine dbr:Designer_drug dbr:Pethidine dbc:4-Phenylpiperidines dbc:Mu-opioid_receptor_agonists dbr:Overdose dbr:LY-88329 dbr:Federal_Analogue_Act dbr:Fentanyl dbr:PEPAP dbc:Synthetic_opioids dbr:Homofentanyl dbr:Opioid dbr:Respiratory_depression dbr:MPPP
dbp:c	23 (xsd:integer)
dbp:casNumber	802832 (xsd:integer)
dbp:chemspiderid	375886 (xsd:integer)
dbp:h	27 (xsd:integer)
dbp:iupacName	[1--4-phenylpiperidin-4-yl] propanoate (en)
dbp:n	1 (xsd:integer)
dbp:o	3 (xsd:integer)
dbp:pubchem	424788 (xsd:integer)
dbp:smiles	CCCOC1C3=CC=CC=C3 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	GCFJWMMGLWBENW-UHFFFAOYSA-N (en)
dbp:wikiPageUsesTemplate	dbt:CAS dbt:Drugbox dbt:Nervous-system-drug-stub dbt:Reflist
dcterms:subject	dbc:4-Phenylpiperidines dbc:Mu-opioid_receptor_agonists dbc:Synthetic_opioids
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug
rdfs:comment	OPPPP (1-(3-Oxo-3-phenylpropyl)-4-phenyl-4-piperidinyl propionate) is an opioid drug related to medicines such as prodine. It is one of several compounds derived from MPPP, the reverse ester of pethidine, which were sold as designer drugs in the 1980s, but have been rarely encountered by law enforcement since the passage of the Federal Analogue Act in 1986. In animal studies it was found to be around 1000x the potency of pethidine, making it several times the potency of fentanyl and with similar hazards of respiratory depression and overdose. It is closely related to numerous compounds made by Janssen et al. for which the structure-activity relationship is well established. (en)
rdfs:label	OPPPP (en)
owl:sameAs	wikidata:OPPPP https://global.dbpedia.org/id/FT8C5 dbr:OPPPP
prov:wasDerivedFrom	wikipedia-en:OPPPP?oldid=1051003778&ns=0
foaf:depiction	wiki-commons:Special:FilePath/OPPPP_Structure.svg
foaf:isPrimaryTopicOf	wikipedia-en:OPPPP
is dbo:wikiPageWikiLink of	dbr:LY-88329 dbr:PEPAP dbr:Homofentanyl
is foaf:primaryTopic of	wikipedia-en:OPPPP