| dbo:abstract
|
- Testosteron undekanoat, atau diketahui pula dengan nama dagang seperti Andriol, Jatenzo (oral), Aveed, atau Nebido (injeksi), adalah obat androgen dan steroid anabolik yang utamanya digunakan untuk mengobati tingkat . Testosteron undekanoat juga digunakan dalam terapi hormon bagi pria transgender. Obat ini dapat digunakan dengan dua hingga tiga kali per hari atau dengan injeksi intramuskular sekali setiap 3,5 hari hingga 2 minggu. Efek samping dari testosteron undekanoat salah satunya adalah gejala seperti timbulnya jerawat, pertumbuhan bulu, suara yang memberat, hipertensi, enzim hati yang meningkat, , serta naiknya libido. Testosteron undekanoat adalah sebuah dan bakal obat dari —ligan dari —sehingga juga merupakan androgen dan steroid anabolik. Testosteron undekanoat memiliki efek androgenik kuat dan efek sedang sehingga berguna dalam memunculkan maskulinisasi serta dalam . Obat ini dinilai sebagai bentuk natural dan bioidentik dari testosteron. Testosteron undekanoat pertama kali diperkenalkan di Tiongkok dalam bentuk injeksi dan di Eropa dalam bentuk obat oral pada tahun 1970-an. Bentuk injeksi mulai tersedia di Eropa sejak awal hingga pertengaha tahun 2000-an dan di Amerika Serikat pada tahun 2014. Testosteron undekanoat merupakan sala satu ester testosteron yang paling banyak digunakan bersama dengan testosteron enantat, testosteron sipionat, dan . Salah satu keunggulan testosteron undekanoat adalah etersediaannya dalam bentuk obat oral dan durasi ketahanannya yang lebih lama jika diberikan lewat injeksi. Selain dari kegunaan medisnya, testosteron undekanoat juga digunakan sebagai . Penggunaan testosteron undekanoat diatur sebagai bukan obat bebas di banyak negara. (in)
- Testosterone undecanoate, sold under the brand names Andriol and Aveed among others, is an androgen and anabolic steroid (AAS) medication that is used mainly in the treatment of low testosterone levels in men, including hormone therapy for transgender men. It is taken by mouth or given by injection into muscle. Side effects of testosterone undecanoate include symptoms of masculinization like acne, increased hair growth, voice changes, hypertension, elevated liver enzymes, hypertriglyceridemia, and increased sexual desire. The drug is a prodrug of testosterone, the biological ligand of the androgen receptor (AR) and hence is an androgen and anabolic steroid. It has strong androgenic effects and moderate anabolic effects, which make it useful for producing masculinization and suitable for androgen replacement therapy. Testosterone undecanoate is a testosterone ester and a prodrug of testosterone in the body. Because of this, it is considered to be a natural and bioidentical form of testosterone. Testosterone undecanoate was introduced in China for use by injection and in the European Union for use by mouth in the 1970s. It became available for use by injection in the European Union in the early to mid 2000s and in the United States in 2014. Formulations for use by mouth are approved in the United States. Along with testosterone enanthate, testosterone cypionate, and testosterone propionate, testosterone undecanoate is one of the most widely used testosterone esters. However, it has advantages over other testosterone esters in that it can be taken by mouth and in that it has a far longer duration when given by injection. In addition to its medical use, testosterone undecanoate is used to improve physique and performance. The drug is a controlled substance in many countries and so non-medical use is generally illicit. (en)
- 운데카노산 테스토스테론(Testosterone undecanoate)는 테스토스테론의 에스테르이다. 남성의 성기능 감퇴 치료, 트랜스남성의 남성화 등 을 할 때 투약한다. 상품명으로 아비드(Aveed), 안드리올(Andriol), 운데스토(Undestor), 네비도(Nebido), 판테스톤(Pantestone), 레스탄돌(Restandol) 등이 있다. 단백동화 스테로이드에 속하므로 운동선수들이 이 약물을 복용하는 것은 금지되어 있다. 한편, 수영선수 박태환이 인천 아시안게임 이전에 이 약물을 투여한 것으로 밝혀져 인천 아시안게임에서 받은 메달이 박탈되는 등의 징계를 받은 사실이 밝혀져 큰 논란을 불러일으켰다. (ko)
- Андриол (Andriol) — лекарственное средство, препарат тестостерона (эфир тестостерона и ундекановой кислоты). Он продаётся под торговыми марками Aveed, Andriol, Undestor, Nebido, Pantestone, Restandol, Cernos Depot, Nebido-R и Reandron 1000. (ru)
|
| dbo:alternativeName
|
- IM: Aveed, Nebido, others (en)
- Oral: Andriol, Jatenzo, others (en)
|
| dbo:casNumber
| |
| dbo:chEBI
| |
| dbo:chEMBL
| |
| dbo:class
| |
| dbo:drugbank
| |
| dbo:fdaUniiCode
| |
| dbo:kegg
| |
| dbo:medlinePlus
| |
| dbo:pubchem
| |
| dbo:thumbnail
| |
| dbo:wikiPageExternalLink
| |
| dbo:wikiPageID
| |
| dbo:wikiPageLength
|
- 31244 (xsd:nonNegativeInteger)
|
| dbo:wikiPageRevisionID
| |
| dbo:wikiPageWikiLink
| |
| dbp:atcPrefix
| |
| dbp:atcSuffix
| |
| dbp:bioavailability
|
- Intramuscular: high (en)
- Oral: 3–7% (en)
|
| dbp:c
| |
| dbp:casNumber
| |
| dbp:chebi
| |
| dbp:chembl
| |
| dbp:chemspiderid
| |
| dbp:class
| |
| dbp:dailymedid
|
- Testosterone_undecanoate (en)
|
| dbp:drugbank
| |
| dbp:eliminationHalfLife
| |
| dbp:excretion
|
- ~90% Urine, 6% feces (en)
|
| dbp:h
| |
| dbp:image
|
- Testosterone undecanoate molecule ball.png (en)
|
| dbp:iupacName
|
- [-10,13-Dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] undecanoate (en)
|
| dbp:kegg
| |
| dbp:legalCa
| |
| dbp:legalUs
| |
| dbp:medlineplus
| |
| dbp:metabolism
| |
| dbp:metabolites
|
- Testosterone, undecanoic acid, metabolites of testosterone (en)
|
| dbp:o
| |
| dbp:pregnancyAu
| |
| dbp:proteinBound
| |
| dbp:pubchem
| |
| dbp:routesOfAdministration
| |
| dbp:smiles
|
- CCCCCCCCCCCO[C@H]1CC[C@@H]2[C@@]1C (en)
|
| dbp:stdinchi
| |
| dbp:stdinchikey
|
- UDSFVOAUHKGBEK-CNQKSJKFSA-N (en)
|
| dbp:synonyms
|
- TU; Testosterone undecylate; Testosterone 17β-undecanoate; ORG-538; CLR-610 (en)
|
| dbp:tradename
|
- IM: Aveed, Nebido, others (en)
- Oral: Andriol, Jatenzo, others (en)
|
| dbp:unii
| |
| dbp:verifiedfields
| |
| dbp:verifiedrevid
| |
| dbp:watchedfields
| |
| dbp:width
| |
| dbp:wikiPageUsesTemplate
| |
| dcterms:subject
| |
| gold:hypernym
| |
| rdf:type
| |
| rdfs:comment
|
- 운데카노산 테스토스테론(Testosterone undecanoate)는 테스토스테론의 에스테르이다. 남성의 성기능 감퇴 치료, 트랜스남성의 남성화 등 을 할 때 투약한다. 상품명으로 아비드(Aveed), 안드리올(Andriol), 운데스토(Undestor), 네비도(Nebido), 판테스톤(Pantestone), 레스탄돌(Restandol) 등이 있다. 단백동화 스테로이드에 속하므로 운동선수들이 이 약물을 복용하는 것은 금지되어 있다. 한편, 수영선수 박태환이 인천 아시안게임 이전에 이 약물을 투여한 것으로 밝혀져 인천 아시안게임에서 받은 메달이 박탈되는 등의 징계를 받은 사실이 밝혀져 큰 논란을 불러일으켰다. (ko)
- Андриол (Andriol) — лекарственное средство, препарат тестостерона (эфир тестостерона и ундекановой кислоты). Он продаётся под торговыми марками Aveed, Andriol, Undestor, Nebido, Pantestone, Restandol, Cernos Depot, Nebido-R и Reandron 1000. (ru)
- Testosteron undekanoat, atau diketahui pula dengan nama dagang seperti Andriol, Jatenzo (oral), Aveed, atau Nebido (injeksi), adalah obat androgen dan steroid anabolik yang utamanya digunakan untuk mengobati tingkat . Testosteron undekanoat juga digunakan dalam terapi hormon bagi pria transgender. Obat ini dapat digunakan dengan dua hingga tiga kali per hari atau dengan injeksi intramuskular sekali setiap 3,5 hari hingga 2 minggu. (in)
- Testosterone undecanoate, sold under the brand names Andriol and Aveed among others, is an androgen and anabolic steroid (AAS) medication that is used mainly in the treatment of low testosterone levels in men, including hormone therapy for transgender men. It is taken by mouth or given by injection into muscle. (en)
|
| rdfs:label
|
- Testosteron undekanoat (in)
- 운데카노산 테스토스테론 (ko)
- Testosterone undecanoate (en)
- Андриол (ru)
|
| rdfs:seeAlso
| |
| owl:sameAs
| |
| prov:wasDerivedFrom
| |
| foaf:depiction
| |
| foaf:isPrimaryTopicOf
| |
| is dbo:wikiPageRedirects
of | |
| is dbo:wikiPageWikiLink
of | |
| is owl:differentFrom
of | |
| is foaf:primaryTopic
of | |
