About: Naloxol

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Naloxol is an opioid antagonist closely related to naloxone. It exists in two isomeric forms, α-naloxol and β-naloxol. α-naloxol is a human metabolite of naloxone. Synthetically, α-naloxol can be prepared from naloxone by reduction of the ketone group, and β-naloxol can be prepared from α-naloxol by a Mitsunobu reaction. Naloxol can be said to be the oxymorphol analogue of naloxone.

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  • Naloxol is an opioid antagonist closely related to naloxone. It exists in two isomeric forms, α-naloxol and β-naloxol. α-naloxol is a human metabolite of naloxone. Synthetically, α-naloxol can be prepared from naloxone by reduction of the ketone group, and β-naloxol can be prepared from α-naloxol by a Mitsunobu reaction. Naloxol can be said to be the oxymorphol analogue of naloxone. (en)
  • ナロキソール（英語:Naloxegol）はナロキソンに類似した、オピオイドに対するアンタゴニスト（）である。α-ナロキソールとβ-ナロキソールの2つの異性体がある。α-ナロキソールはヒトがナロキソンを代謝したときに生成する物質である。α-ナロキソールはケトンを還元して合成し、β-ナロキソールはα-ナロキソールを光延反応によって変換する。 (ja)
dbo:iupacName
  • α-naloxol: (4R,4aS,7S,7aR,12bS)-3-allyl-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol (en)
  • β-naloxol: (4R,4aS,7R,7aR,12bS)-3-allyl-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol (en)
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  • α-naloxol (en)
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  • β-naloxol (en)
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  • α-naloxol (en)
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  • β-naloxol (en)
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  • alpha-Naloxol.svg (en)
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  • beta-Naloxol.svg (en)
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  • α-naloxol: -3-allyl-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol (en)
  • β-naloxol: -3-allyl-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol (en)
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  • changed (en)
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  • changed (en)
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  • Naloxol is an opioid antagonist closely related to naloxone. It exists in two isomeric forms, α-naloxol and β-naloxol. α-naloxol is a human metabolite of naloxone. Synthetically, α-naloxol can be prepared from naloxone by reduction of the ketone group, and β-naloxol can be prepared from α-naloxol by a Mitsunobu reaction. Naloxol can be said to be the oxymorphol analogue of naloxone. (en)
  • ナロキソール（英語:Naloxegol）はナロキソンに類似した、オピオイドに対するアンタゴニスト（）である。α-ナロキソールとβ-ナロキソールの2つの異性体がある。α-ナロキソールはヒトがナロキソンを代謝したときに生成する物質である。α-ナロキソールはケトンを還元して合成し、β-ナロキソールはα-ナロキソールを光延反応によって変換する。 (ja)
rdfs:label
  • ナロキソール (ja)
  • Naloxol (en)
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