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- Von einer Mikrometastase spricht man, wenn ein Zellverband eine Größe von 0,2 bis 2 mm erreicht hat, was ein Kriterium für einen bösartigen Tumor durch das invasive Wachstumsverhalten darstellt. Das heißt, dass der Tumor mit seinem Wachstum Organgrenzen überschreitet. So werden dann auch Blut- und Lymphgefäße infiltriert. Auf diese Weise siedeln sich Tumorzellen ab, sie disseminieren. (Dissemination=Aussaat/Ausbreitung) Diese disseminierten Tumorzellen (DTZ) sind dann z. B. in einem Lymphknoten immunchemisch nachweisbar. Auf dem hämatogenen Weg finden sich DTZ im Knochenmark wieder, hier sind sie ebenfalls immunchemisch nachweisbar. (de)
- A micrometastasis is a small collection of cancer cells that has been shed from the original tumor and spread to another part of the body through the lymphovascular system. Micrometastases are too few, in size and quantity, to be picked up in a screening or diagnostic test, and therefore cannot be seen with imaging tests such as a mammogram, MRI, ultrasound, PET, or CT scans. These migrant cancer cells may group together to form a second tumor, which is so small that it can only be seen under a microscope. Approximately ninety percent of people who die from cancer die from metastatic disease, since these cells are so challenging to detect. It is important for these cancer cells to be treated immediately after discovery, in order to prevent the relapse (regrowth of the cancer) and the likely death of the patient. (en)
- Una micrometastasi è una forma di metastasi (masse tumorali che si spostano dai loro siti di origine verso altre regioni del corpo) dove i tumori neoformati sono troppo minuscoli per poter essere scoperti. La terapia adiuvante chemioterapica e radioterapica è finalizzata all'uccisione di qualsiasi micrometastasi, prevenendo dunque una recidiva (ricrescita delle cellule tumorali) e pertanto una probabile morte del paziente. Un riconoscimento precoce delle micrometastasi potrebbe aiutare nella selezione dei pazienti che potrebbero beneficiare della terapia adiuvante. (it)
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- Von einer Mikrometastase spricht man, wenn ein Zellverband eine Größe von 0,2 bis 2 mm erreicht hat, was ein Kriterium für einen bösartigen Tumor durch das invasive Wachstumsverhalten darstellt. Das heißt, dass der Tumor mit seinem Wachstum Organgrenzen überschreitet. So werden dann auch Blut- und Lymphgefäße infiltriert. Auf diese Weise siedeln sich Tumorzellen ab, sie disseminieren. (Dissemination=Aussaat/Ausbreitung) Diese disseminierten Tumorzellen (DTZ) sind dann z. B. in einem Lymphknoten immunchemisch nachweisbar. Auf dem hämatogenen Weg finden sich DTZ im Knochenmark wieder, hier sind sie ebenfalls immunchemisch nachweisbar. (de)
- Una micrometastasi è una forma di metastasi (masse tumorali che si spostano dai loro siti di origine verso altre regioni del corpo) dove i tumori neoformati sono troppo minuscoli per poter essere scoperti. La terapia adiuvante chemioterapica e radioterapica è finalizzata all'uccisione di qualsiasi micrometastasi, prevenendo dunque una recidiva (ricrescita delle cellule tumorali) e pertanto una probabile morte del paziente. Un riconoscimento precoce delle micrometastasi potrebbe aiutare nella selezione dei pazienti che potrebbero beneficiare della terapia adiuvante. (it)
- A micrometastasis is a small collection of cancer cells that has been shed from the original tumor and spread to another part of the body through the lymphovascular system. Micrometastases are too few, in size and quantity, to be picked up in a screening or diagnostic test, and therefore cannot be seen with imaging tests such as a mammogram, MRI, ultrasound, PET, or CT scans. These migrant cancer cells may group together to form a second tumor, which is so small that it can only be seen under a microscope. Approximately ninety percent of people who die from cancer die from metastatic disease, since these cells are so challenging to detect. It is important for these cancer cells to be treated immediately after discovery, in order to prevent the relapse (regrowth of the cancer) and the likel (en)
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- Mikrometastase (de)
- Micrometastasi (it)
- Micrometastasis (en)
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