About: Medrogestone

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Medrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders. It is available both alone and in combination with an estrogen. It is taken by mouth. Medrogestone was described as early as 1963 and was introduced for medical use by at least 1966. It has mostly been discontinued and remains available only in a few countries.

Property Value
dbo:abstract
  • Medrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders. It is available both alone and in combination with an estrogen. It is taken by mouth. Medrogestone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has weak antiandrogenic, glucocorticoid, and antimineralocorticoid activity and no other important hormonal activity. Due to its progestogenic activity, medrogestone has antigonadotropic effects. Medrogestone was described as early as 1963 and was introduced for medical use by at least 1966. It has mostly been discontinued and remains available only in a few countries. (en)
dbo:alternativeName
  • Colprone, others (en)
dbo:atcCode
  • (withestrogen)
dbo:casNumber
  • 977-79-7
dbo:class
dbo:drugbank
  • DB09124
dbo:fdaUniiCode
  • 077DN93G5B
dbo:kegg
  • D04885
dbo:pubchem
  • 9949848
dbo:thumbnail
dbo:wikiPageID
  • 23484653 (xsd:integer)
dbo:wikiPageLength
  • 24619 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1121639853 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • G03 (en)
dbp:atcSuffix
  • DB03 (en)
dbp:bioavailability
  • Nearly 100% (en)
dbp:c
  • 23 (xsd:integer)
dbp:casNumber
  • 977 (xsd:integer)
dbp:chemspiderid
  • 8125459 (xsd:integer)
dbp:class
dbp:drugbank
  • DB09124 (en)
dbp:eliminationHalfLife
  • -129600.0
dbp:h
  • 32 (xsd:integer)
dbp:iupacName
  • -17 (xsd:integer)
dbp:kegg
  • D04885 (en)
dbp:legalStatus
  • Rx-only (en)
dbp:metabolism
  • Hepatic (en)
dbp:o
  • 2 (xsd:integer)
dbp:pregnancyCategory
  • X (en)
dbp:proteinBound
  • 95 (xsd:integer)
dbp:pubchem
  • 9949848 (xsd:integer)
dbp:routesOfAdministration
dbp:smiles
  • O=C4\C=C3\CC (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • HCFSGRMEEXUOSS-JXEXPEPMSA-N (en)
dbp:synonyms
  • Metrogestone; Medrogesterone; AY-62022, NSC-123018, R-13615; 6,17α-Dimethyl-6-dehydroprogesterone; 6,17α-Dimethyl-4,6-pregnadiene-3,20-dione (en)
dbp:title
dbp:titlestyle
  • background:#ccccff (en)
dbp:tradename
  • Colprone, others (en)
dbp:unii
  • 77 (xsd:integer)
dbp:width
  • 200 (xsd:integer)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Medrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders. It is available both alone and in combination with an estrogen. It is taken by mouth. Medrogestone was described as early as 1963 and was introduced for medical use by at least 1966. It has mostly been discontinued and remains available only in a few countries. (en)
rdfs:label
  • Medrogestone (en)
rdfs:seeAlso
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
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