About: Lilotomab

An Entity of Type: monoclonal antibody, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Lilotomab (formerly tetulomab, HH1) is a murine monoclonal antibody against CD37, a glycoprotein which is expressed on the surface of mature human B cells. It was generated at the Norwegian Radium Hospital.

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dbo:abstract
  • Lilotomab (formerly tetulomab, HH1) is a murine monoclonal antibody against CD37, a glycoprotein which is expressed on the surface of mature human B cells. It was generated at the Norwegian Radium Hospital. As of 2016 it was under development by the Norwegian company Nordic Nanovector ASA as a radioimmunotherapeutic in which lilotomab is conjugated to the beta radiation-emitting isotope lutetium-177 by means of a linker called satetraxetan, a derivative of DOTA. This compound is called 177Lu-HH1 or lutetium (177Lu) lilotomab satetraxetan (trade name Betalutin). As of 2016, a phase 1/2 clinical trial in people with non-Hodgkin lymphoma was underway. (en)
dbo:casNumber
  • (lutetium (177Lu) lilotomab satetraxetan)
  • 1453362-55-4
dbo:fdaUniiCode
  • 58I6YNR7BV
dbo:kegg
  • D12125
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  • 39308546 (xsd:integer)
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  • 4589 (xsd:nonNegativeInteger)
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  • 1049617216 (xsd:integer)
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  • none (en)
dbp:casNumber
  • 1453362 (xsd:integer)
dbp:chemspiderid
  • none (en)
dbp:kegg
  • D12125 (en)
dbp:mabType
  • mab (en)
dbp:source
  • o (en)
dbp:synonyms
  • Tetulomab, HH1 (en)
dbp:target
dbp:type
  • mab (en)
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  • 58 (xsd:integer)
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rdfs:comment
  • Lilotomab (formerly tetulomab, HH1) is a murine monoclonal antibody against CD37, a glycoprotein which is expressed on the surface of mature human B cells. It was generated at the Norwegian Radium Hospital. (en)
rdfs:label
  • Lilotomab (en)
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