About: Lupitidine

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Lupitidine (INN; lupitidine hydrochloride (USAN); development code SKF-93479) is a long-acting H2 receptor antagonist developed by Smith, Kline & French and described as an antiulcerogenic that was never marketed. It was shown to inhibit nocturnal gastric acid secretion and, in experiments on rodents, produced diffuse neuroendocrine cell hyperplasia and an increase in multifocal glandular hyperplasia due to hypergastrinemia resulting from the pharmacological suppression of gastric acid secretion.

thumbnail
Property Value
dbo:abstract
  • Lupitidine (INN; lupitidine hydrochloride (USAN); development code SKF-93479) is a long-acting H2 receptor antagonist developed by Smith, Kline & French and described as an antiulcerogenic that was never marketed. It was shown to inhibit nocturnal gastric acid secretion and, in experiments on rodents, produced diffuse neuroendocrine cell hyperplasia and an increase in multifocal glandular hyperplasia due to hypergastrinemia resulting from the pharmacological suppression of gastric acid secretion. (en)
dbo:casNumber
  • 83903-06-4
dbo:fdaUniiCode
  • WF028DWK9N
dbo:kegg
  • D04794
dbo:pubchem
  • 51671
dbo:thumbnail
dbo:wikiPageID
  • 27162158 (xsd:integer)
dbo:wikiPageLength
  • 3348 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1082622342 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • None (en)
dbp:c
  • 21 (xsd:integer)
dbp:casNumber
  • 83903 (xsd:integer)
dbp:chemspiderid
  • 3577726 (xsd:integer)
dbp:h
  • 27 (xsd:integer)
dbp:iupacName
  • 2 (xsd:integer)
dbp:kegg
  • D04794 (en)
dbp:n
  • 5 (xsd:integer)
dbp:o
  • 2 (xsd:integer)
dbp:pubchem
  • 51671 (xsd:integer)
dbp:s
  • 1 (xsd:integer)
dbp:smiles
  • CC1=NC=CCC2=CN=CNCCSCC3=CC=CCN (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • CZTPLYMKHNEVHO-UHFFFAOYSA-N (en)
dbp:unii
  • WF028DWK9N (en)
dbp:width
  • 260 (xsd:integer)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Lupitidine (INN; lupitidine hydrochloride (USAN); development code SKF-93479) is a long-acting H2 receptor antagonist developed by Smith, Kline & French and described as an antiulcerogenic that was never marketed. It was shown to inhibit nocturnal gastric acid secretion and, in experiments on rodents, produced diffuse neuroendocrine cell hyperplasia and an increase in multifocal glandular hyperplasia due to hypergastrinemia resulting from the pharmacological suppression of gastric acid secretion. (en)
rdfs:label
  • Lupitidine (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License