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In organometallic chemistry, metal–halogen exchange is a fundamental reaction that converts a organic halide into an organometallic product. The reaction commonly involves the use of electropositive metals (Li, Na, Mg) and organochlorides, bromides, and iodides. Particularly well-developed is the use of metal–halogen exchange for the preparation of organolithium compounds.

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  • In organometallic chemistry, metal–halogen exchange is a fundamental reaction that converts a organic halide into an organometallic product. The reaction commonly involves the use of electropositive metals (Li, Na, Mg) and organochlorides, bromides, and iodides. Particularly well-developed is the use of metal–halogen exchange for the preparation of organolithium compounds. (en)
  • 在金属有机化学中,金属-卤素交换反应是将卤代烃转化为有机金属化合物的基本反应,其中研究较多的是利用金属-卤素交换反应制备有机锂化合物。反应速率以碘、溴、氯递减,烷基和芳基氟化物一般难以反应。锂-卤素交换受动力学控制,主要受有机锂试剂对应的碳负离子中间体的稳定性(sp > sp2 > sp3)影响。除锂外,锌、镁也可发生金属-卤素交换反应。 (zh)
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  • In organometallic chemistry, metal–halogen exchange is a fundamental reaction that converts a organic halide into an organometallic product. The reaction commonly involves the use of electropositive metals (Li, Na, Mg) and organochlorides, bromides, and iodides. Particularly well-developed is the use of metal–halogen exchange for the preparation of organolithium compounds. (en)
  • 在金属有机化学中,金属-卤素交换反应是将卤代烃转化为有机金属化合物的基本反应,其中研究较多的是利用金属-卤素交换反应制备有机锂化合物。反应速率以碘、溴、氯递减,烷基和芳基氟化物一般难以反应。锂-卤素交换受动力学控制,主要受有机锂试剂对应的碳负离子中间体的稳定性(sp > sp2 > sp3)影响。除锂外,锌、镁也可发生金属-卤素交换反应。 (zh)
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  • Metal–halogen exchange (en)
  • 金属-卤素交换反应 (zh)
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