About: Levormeloxifene

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Levormeloxifene (INN; developmental code names 6720-CDRI, NNC-460020) is a selective estrogen receptor modulator (SERM) which was being developed as an alternative to estrogen replacement therapy for the treatment and prevention of postmenopausal bone loss but did not complete development and hence was never marketed. The development was stopped because of a high incidence of gynecological side effects during clinical trials. Levormeloxifene is the levorotatory enantiomer of ormeloxifene, which, in contrast, has been marketed, though rather as a hormonal contraceptive.

Property	Value
dbo:abstract	Levormeloxifene (INN; developmental code names 6720-CDRI, NNC-460020) is a selective estrogen receptor modulator (SERM) which was being developed as an alternative to estrogen replacement therapy for the treatment and prevention of postmenopausal bone loss but did not complete development and hence was never marketed. The development was stopped because of a high incidence of gynecological side effects during clinical trials. Levormeloxifene is the levorotatory enantiomer of ormeloxifene, which, in contrast, has been marketed, though rather as a hormonal contraceptive. (en)
dbo:casNumber	78994-23-7
dbo:chEMBL	301327
dbo:fdaUniiCode	9512UKZ352
dbo:pubchem	35805
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dbp:smiles	OCCN5CCCC5 (en)
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dbp:stdinchikey	XZEUAXYWNKYKPL-WDYNHAJCSA-N (en)
dbp:synonyms	Levomeloxifene; 6720-CDRI; NNC-460020 (en)
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dbp:verifiedfields	changed (en)
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dcterms:subject	dbc:Abandoned_drugs dbc:Ethers dbc:Pyrrolidines dbc:Benzopyrans dbc:Selective_estrogen_receptor_modulators
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rdfs:comment	Levormeloxifene (INN; developmental code names 6720-CDRI, NNC-460020) is a selective estrogen receptor modulator (SERM) which was being developed as an alternative to estrogen replacement therapy for the treatment and prevention of postmenopausal bone loss but did not complete development and hence was never marketed. The development was stopped because of a high incidence of gynecological side effects during clinical trials. Levormeloxifene is the levorotatory enantiomer of ormeloxifene, which, in contrast, has been marketed, though rather as a hormonal contraceptive. (en)
rdfs:label	Levormeloxifene (en)
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