The Keyesville massacre occurred on April 19, 1863, in Tulare County, now Kern County, California, during the Owens Valley Indian War. White settlers and a detachment of the 2nd California Volunteer Cavalry under Captain Moses A. McLaughlin, killed 35 Tübatulabal and Owens Valley Paiute men, "about ten miles from Keysville [sic], upon the right bank of Kern River".