Karimpuzha Wildlife Sanctuary is a Wildlife sanctuary near Nilambur, Malappuram district in the Indian state of Kerala. It is declared as a wildlife sanctuary on 3 July 2020. It covers an area of 227.97 sq km and comprises the New Amarambalam Reserved Forest and Vadakkekotta vested forest, except the Manjeri colony of the Cholanaikar tribe. It forms a portion of the Nilgiri Biosphere Reserve.