The enzyme juvenile hormone esterase (EC 3.1.1.59, systematic name methyl-(2E,6E,10R)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase, JH esterase) catalyzes the hydrolysis of juvenile hormone: (1) juvenile hormone I + H2O = juvenile hormone I acid + methanol(2) juvenile hormone III + H2O = juvenile hormone III acid + methanol