Lafayette Fresco Thompson Jr. (June 6, 1902 – November 20, 1968) was an American Major League Baseball second baseman and executive. Thompson was born in Centreville, Alabama. In 1916, when he was 14, his family moved to New York City, where Thompson attended George Washington High School and Columbia University. At Columbia, he was a football teammate of Lou Gehrig's, but Thompson left the school to turn professional before he could join Gehrig on the Lions' baseball team.