An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Flortaucipir (18F), sold under the brand name Tauvid, is a radioactive diagnostic agent indicated for use with positron emission tomography (PET) imaging to image the brain. The most common adverse reactions include headache, injection site pain and increased blood pressure. It is the first drug used to help image a distinctive characteristic of Alzheimer's disease in the brain called tau pathology. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.

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dbo:abstract
  • Flortaucipir (18F), sold under the brand name Tauvid, is a radioactive diagnostic agent indicated for use with positron emission tomography (PET) imaging to image the brain. The most common adverse reactions include headache, injection site pain and increased blood pressure. Two proteins – tau and amyloid – are recognized as hallmarks of Alzheimer's disease. In people with Alzheimer's disease, pathological forms of tau proteins develop inside neurons in the brain, creating neurofibrillary tangles. After flortaucipir (18F) is administered intravenously, it binds to sites in the brain associated with this tau protein misfolding. The brain can then be imaged with a PET scan to help identify the presence of tau pathology. It is the first drug used to help image a distinctive characteristic of Alzheimer's disease in the brain called tau pathology. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. (en)
  • Флортауципир (18F) — радиофармацевтический препарат для диагностики болезни Альцгеймера. Одобрен для применения: США (2020). (ru)
dbo:alternativeName
  • Tauvid (en)
dbo:casNumber
  • 1522051-90-6
dbo:chEMBL
  • 3545253
dbo:chemicalFormula
  • C16H10[18F]N3
dbo:drugbank
  • DB14914
dbo:fdaUniiCode
  • T1JP1KYU9O
dbo:kegg
  • D11210
dbo:pubchem
  • 70957463
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  • None (en)
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  • 1522051 (xsd:integer)
dbp:chembl
  • 3545253 (xsd:integer)
dbp:chemicalFormula
  • C16H10[18F]N3 (en)
dbp:chemspiderid
  • 32701063 (xsd:integer)
dbp:dailymedid
  • Flortaucipir (en)
dbp:drugName
  • Flortaucipir (en)
dbp:drugbank
  • DB14914 (en)
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  • 7 (xsd:integer)
dbp:kegg
  • D11210 (en)
dbp:legalUs
  • Rx-only (en)
dbp:licenceUs
  • Tauvid (en)
dbp:molecularWeight
  • 262.270000 (xsd:double)
dbp:pronounce
  • flor tau' si pir 18 F (en)
dbp:pubchem
  • 70957463 (xsd:integer)
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  • C1=CC2=CNC4=C2C=NC=C4 (en)
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  • 1 (xsd:integer)
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  • GETAAWDSFUCLBS-SJPDSGJFSA-N (en)
dbp:synonyms
  • 18 (xsd:integer)
dbp:tradename
  • Tauvid (en)
dbp:unii
  • T1JP1KYU9O (en)
dbp:usan
  • flortaucipir F 18 (en)
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  • Флортауципир (18F) — радиофармацевтический препарат для диагностики болезни Альцгеймера. Одобрен для применения: США (2020). (ru)
  • Flortaucipir (18F), sold under the brand name Tauvid, is a radioactive diagnostic agent indicated for use with positron emission tomography (PET) imaging to image the brain. The most common adverse reactions include headache, injection site pain and increased blood pressure. It is the first drug used to help image a distinctive characteristic of Alzheimer's disease in the brain called tau pathology. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. (en)
rdfs:label
  • Flortaucipir (18F) (en)
  • Flortaucipir (18F) (ru)
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foaf:depiction
foaf:isPrimaryTopicOf
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  • Flortaucipir (18F) (en)
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