Escherichia virus G4 is a bacteriophage that infects E. coli. First isolated in 1973, the phage was originally isolated from samples of raw sewage and has 5,577 nucleotides. Its isometric capsid contains a single-stranded circular genome of about 5.5 kbp. Phage G4 bears high genetic and structural similarity to the phage ΦX174, though the two phage genomes are up to 39 percent different by sequence.
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