| dbo:abstract
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- The Early 35 kDa protein, or P35 in short, is a baculoviral protein that inhibits apoptosis in the cells infected by the virus. Although baculoviruses infect only invertebrates in nature, ectopic expression of P35 in vertebrate animals and cells also results in inhibition of apoptosis, thus indicating a universal mechanism. P35 has been shown to be a caspase inhibitor with a very wide spectrum of activity both in regard to inhibited caspase types and to species in which the mechanism is conserved. (en)
- La protéine p35 est une protéine virale anti-apoptotique qui a un poids moléculaire de 35 kD et possède un total de 299 acides aminés. Elle est située dans le cytoplasme des cellules qu'elle infecte et associée aux membranes intracellulaires des mitochondries et du réticulum endoplasmique. (fr)
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| dbo:wikiPageID
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- 10733 (xsd:nonNegativeInteger)
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| dbo:wikiPageRevisionID
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| dbo:wikiPageWikiLink
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| dbp:caption
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- P35 structure by Fisher et al. 1999 (en)
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| dbp:chromosome
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| dbp:entrezchromosome
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- NC_001623.1 (en)
- NC_001962.1 (en)
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| dbp:entrezgene
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- 1403968 (xsd:integer)
- 1488744 (xsd:integer)
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| dbp:genlocEnd
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- 106822 (xsd:integer)
- 117391 (xsd:integer)
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| dbp:genlocStart
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- 105923 (xsd:integer)
- 116492 (xsd:integer)
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| dbp:name
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- Early 35 kDa protein (en)
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| dbp:organism
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- Autographa californica nuclear polyhedrosis virus (en)
- Bombyx mori nuclear polyhedrosis virus (en)
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| dbp:pdb
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| dbp:refseqmrna
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- NC_001623.1 (en)
- NC_001962.1 (en)
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| dbp:refseqprotein
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- NP_047533.1 (en)
- NP_054165.1 (en)
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| dbp:symbol
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| dbp:taxid
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- 46015 (xsd:integer)
- 271108 (xsd:integer)
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| dbp:uniprot
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| dbp:wikiPageUsesTemplate
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| dcterms:subject
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| gold:hypernym
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| rdf:type
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| rdfs:comment
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- The Early 35 kDa protein, or P35 in short, is a baculoviral protein that inhibits apoptosis in the cells infected by the virus. Although baculoviruses infect only invertebrates in nature, ectopic expression of P35 in vertebrate animals and cells also results in inhibition of apoptosis, thus indicating a universal mechanism. P35 has been shown to be a caspase inhibitor with a very wide spectrum of activity both in regard to inhibited caspase types and to species in which the mechanism is conserved. (en)
- La protéine p35 est une protéine virale anti-apoptotique qui a un poids moléculaire de 35 kD et possède un total de 299 acides aminés. Elle est située dans le cytoplasme des cellules qu'elle infecte et associée aux membranes intracellulaires des mitochondries et du réticulum endoplasmique. (fr)
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| rdfs:label
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- Early 35 kDa protein (en)
- P35 (protéine) (fr)
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| prov:wasDerivedFrom
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| foaf:depiction
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| foaf:isPrimaryTopicOf
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| is dbo:wikiPageWikiLink
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| is foaf:primaryTopic
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