Diana O. Perkins is an American professor at the University of North Carolina's (UNC) School of Medicine where she teaches psychiatry; she is a fellow with outreach roles. Her research involves early diagnosis and treatment of schizophrenia. She is noted for publishing a study that demonstrated that using a polygenic risk score (PRS) based on data from genome-wide association studies improved the psychosis risk prediction in persons meeting clinical high-risk criteria.
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