About: CMX521

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

CMX521 is an antiviral drug discovered by Chimerix, which was developed for the treatment of norovirus, though it also shows efficacy against related viral diarrheas such as rotovirus and some sapoviruses, astroviruses and adenoviruses. It is a nucleoside analogue which acts as an inhibitor of viral RNA-dependant RNA polymerase.

Property	Value
dbo:abstract	CMX521 is an antiviral drug discovered by Chimerix, which was developed for the treatment of norovirus, though it also shows efficacy against related viral diarrheas such as rotovirus and some sapoviruses, astroviruses and adenoviruses. It is a nucleoside analogue which acts as an inhibitor of viral RNA-dependant RNA polymerase. (en)
dbo:casNumber	2077178-99-3
dbo:fdaUniiCode	76US2C2X3F
dbo:pubchem	126520436
dbo:thumbnail	wiki-commons:Special:FilePath/CMX521_structure.png?width=300
dbo:wikiPageID	63830786 (xsd:integer)
dbo:wikiPageLength	2591 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1123395729 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Nucleoside_analogue dbc:Antiviral_drugs dbr:Norovirus dbr:GS-441524 dbr:NITD008 dbc:Anti–RNA_virus_drugs dbr:Adenovirus dbr:Astrovirus dbr:Antiviral dbr:Sapovirus dbr:Polymerase dbr:Sangivamycin dbr:Rotovirus
dbp:c	13 (xsd:integer)
dbp:casNumber	2077178 (xsd:integer)
dbp:h	17 (xsd:integer)
dbp:iupacName	4 (xsd:integer)
dbp:legalUs	Investigational drug (en)
dbp:molecularWeight	323.300000 (xsd:double)
dbp:n	5 (xsd:integer)
dbp:o	5 (xsd:integer)
dbp:pubchem	126520436 (xsd:integer)
dbp:smiles	CC1=NCN (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	PMQFVTNOZQVIOK-HTVVRFAVSA-N (en)
dbp:unii	76 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Fdacite dbt:RNA_antivirals dbt:Antiinfective-drug-stub
dcterms:subject	dbc:Antiviral_drugs dbc:Anti–RNA_virus_drugs
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug
rdfs:comment	CMX521 is an antiviral drug discovered by Chimerix, which was developed for the treatment of norovirus, though it also shows efficacy against related viral diarrheas such as rotovirus and some sapoviruses, astroviruses and adenoviruses. It is a nucleoside analogue which acts as an inhibitor of viral RNA-dependant RNA polymerase. (en)
rdfs:label	CMX521 (en)
owl:sameAs	wikidata:CMX521 https://global.dbpedia.org/id/C9M5B dbr:CMX521
prov:wasDerivedFrom	wikipedia-en:CMX521?oldid=1123395729&ns=0
foaf:depiction	wiki-commons:Special:FilePath/CMX521_structure.png
foaf:isPrimaryTopicOf	wikipedia-en:CMX521
is dbo:wikiPageWikiLink of	dbr:GS-441524 dbr:C13H17N5O5 dbr:Sangivamycin
is foaf:primaryTopic of	wikipedia-en:CMX521