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- Chronic kidney disease of unknown etiology (CKDu) is an increasing health concern in Sri Lanka. CKDu is recognized as chronic kidney disease without the usual associated causative factors. The first cases of CKDu were reported in Sri Lanka's North Central Province (NCP). Chronic kidney disease (listed under diseases of the urinary tract), was identified as the 8th leading cause of in-hospital mortality in Sri Lanka, and the leading cause of death in Anuradhapura and Polonnaruwa in 2016. This rise in mortality coincided with the increasing cases of CKDu seen across the country. Studies have shown an estimated 70,000 CKDu patients in high risk areas. Various possible causes for CKDu in Sri Lankans have been investigated, including poisoning from metals, cyanobacteria toxins, agrochemicals, and heat stress, but no definite causes have been identified. There have been several other geographic areas in which CKDu has emerged, such as Africa, Central America (see Mesoamerican nephropathy), and Asia. Due to similar signs and symptoms of CKDu in these areas, CKDu is also referred to as Chronic Interstitial Nephritis in Agricultural Communities. (en)
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- Chronic kidney disease of unknown etiology (CKDu) is an increasing health concern in Sri Lanka. CKDu is recognized as chronic kidney disease without the usual associated causative factors. The first cases of CKDu were reported in Sri Lanka's North Central Province (NCP). Chronic kidney disease (listed under diseases of the urinary tract), was identified as the 8th leading cause of in-hospital mortality in Sri Lanka, and the leading cause of death in Anuradhapura and Polonnaruwa in 2016. This rise in mortality coincided with the increasing cases of CKDu seen across the country. Studies have shown an estimated 70,000 CKDu patients in high risk areas. Various possible causes for CKDu in Sri Lankans have been investigated, including poisoning from metals, cyanobacteria toxins, agrochemicals, a (en)
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