About: Alpha Arrestin

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The arrestin family of proteins is subdivided into α-arrestins (also referred to as arrestin-related trafficking adaptors (ARTs) or arrestin-like yeast proteins (ALYs) in yeast or ARRDCs (arrestin domain containing proteins) in mammals, β-arrestins (also referred to as visual and non-visual arrestins) and Vps26-like arrestins proteins. The α-Arrestins are an ancestral branch of the larger arrestin family of proteins and they are conserved across eukaryotes but are best characterized in the budding yeast Saccharomyces cerevisiae; to-date there are 6 α-arrestins identified in mammalian cells (arrestin-domain containing proteins [ARRDC]1-5 and thioredoxin interacting protein [TXNIP]) and 14 α-arrestins identified in the budding yeast Saccharomyces cerevisiae. The yeast α-arrestin family compr

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  • The arrestin family of proteins is subdivided into α-arrestins (also referred to as arrestin-related trafficking adaptors (ARTs) or arrestin-like yeast proteins (ALYs) in yeast or ARRDCs (arrestin domain containing proteins) in mammals, β-arrestins (also referred to as visual and non-visual arrestins) and Vps26-like arrestins proteins. The α-Arrestins are an ancestral branch of the larger arrestin family of proteins and they are conserved across eukaryotes but are best characterized in the budding yeast Saccharomyces cerevisiae; to-date there are 6 α-arrestins identified in mammalian cells (arrestin-domain containing proteins [ARRDC]1-5 and thioredoxin interacting protein [TXNIP]) and 14 α-arrestins identified in the budding yeast Saccharomyces cerevisiae. The yeast α-arrestin family comprises Ldb19/Art1, Ecm21/Art2, Aly1/Art6, Aly2/Art3, Rod1/Art4, Rog3/Art7, Art5, Csr2/Art8, Rim8/Art9, Art10, Bul1, Bul2, Bul3 and Spo23. The best characterized α-arrestin function to date is their endocytic regulation of plasma membrane proteins, including G-protein coupled receptors (GPCRs) and nutrient transporters (reviewed in). α-Arrestins control endocytosis of these membrane proteins in response to cellular stressors, including nutrient or metal ion excess. (en)
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  • The arrestin family of proteins is subdivided into α-arrestins (also referred to as arrestin-related trafficking adaptors (ARTs) or arrestin-like yeast proteins (ALYs) in yeast or ARRDCs (arrestin domain containing proteins) in mammals, β-arrestins (also referred to as visual and non-visual arrestins) and Vps26-like arrestins proteins. The α-Arrestins are an ancestral branch of the larger arrestin family of proteins and they are conserved across eukaryotes but are best characterized in the budding yeast Saccharomyces cerevisiae; to-date there are 6 α-arrestins identified in mammalian cells (arrestin-domain containing proteins [ARRDC]1-5 and thioredoxin interacting protein [TXNIP]) and 14 α-arrestins identified in the budding yeast Saccharomyces cerevisiae. The yeast α-arrestin family compr (en)
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  • Alpha Arrestin (en)
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