The 2022 Tennessee Lottery 250 was the fifteenth stock car race of the 2022 NASCAR Xfinity Series and the 13th iteration of the event. The race was held on Saturday, June 25, 2022, in Gladeville, Tennessee at Nashville Superspeedway, a 1.333 miles (2.145 km) permanent D-shaped racetrack. The race took it's scheduled 188 laps to complete. Justin Allgaier, driving for JR Motorsports, put on a dominating performance, winning both stages, and leading 134 laps for his 18th career Xfinity Series win, along with his second of the season. To fill out the podium, Trevor Bayne, driving for Joe Gibbs Racing, and Riley Herbst, driving for Stewart-Haas Racing, would finish 2nd and 3rd, respectively.