About: 1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole (4,5-DHP-DMT) is a tricyclic tryptamine derivative which acts as a potent and reasonably selective partial agonist for the serotonin receptor 5-HT2A, with a Ki of 17.0 nM, and moderate selectivity over related serotonin receptors. It has lower 5-HT2 affinity and efficacy than the related compound AL-37350A, but higher lipophilicity.

Property	Value
dbo:abstract	1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole (4,5-DHP-DMT) is a tricyclic tryptamine derivative which acts as a potent and reasonably selective partial agonist for the serotonin receptor 5-HT2A, with a Ki of 17.0 nM, and moderate selectivity over related serotonin receptors. It has lower 5-HT2 affinity and efficacy than the related compound AL-37350A, but higher lipophilicity. (en)
dbo:casNumber	135360-97-3
dbo:chEMBL	412876
dbo:fdaUniiCode	UW9YPK64EU
dbo:pubchem	15011385
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dbp:c	15 (xsd:integer)
dbp:casNumber	135360 (xsd:integer)
dbp:chembl	412876 (xsd:integer)
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dbp:smiles	CNCCc1c[nH]c3ccc2OCCCc2c13 (en)
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rdfs:comment	1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole (4,5-DHP-DMT) is a tricyclic tryptamine derivative which acts as a potent and reasonably selective partial agonist for the serotonin receptor 5-HT2A, with a Ki of 17.0 nM, and moderate selectivity over related serotonin receptors. It has lower 5-HT2 affinity and efficacy than the related compound AL-37350A, but higher lipophilicity. (en)
rdfs:label	1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole (en)
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foaf:name	4,5-DHP-DMT (en)
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