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Statements

Subject Item
dbr:MiR-150
rdfs:label
MiR-150
rdfs:comment
miR-150 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interference. miR-150 functions in hematopoiesis; it regulates genes whose downstream products encourage differentiating stem cells towards becoming megakaryocytes rather than erythrocytes. It is also thought to control B and T cell differentiation, alongside mir-155.
dbp:name
miR-150
foaf:depiction
n4:Mir-150_SS.png
dcterms:subject
dbc:MicroRNA
dbo:wikiPageID
33021284
dbo:wikiPageRevisionID
1083114975
dbo:wikiPageWikiLink
dbr:Mammalia dbr:Gastric_cancer dbr:Hepatocellular_carcinoma dbr:Dicer dbr:Mammal dbr:Mir-155 dbc:MicroRNA dbr:RNA_interference dbr:Osteosarcoma dbr:Erythrocyte dbr:Megakaryocyte dbr:Cancer dbr:Sepsis dbr:MicroRNA dbr:Hematopoiesis dbr:RNA-induced_silencing_complex dbr:T_cell dbr:Biomarker dbr:B_cell dbr:Human dbr:Therapeutic dbr:Nucleotide dbr:Secondary_structure
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dbt:MiRNA_precursor_families dbt:Refbegin dbt:Reflist dbt:Infobox_rfam dbt:Refend dbt:Lowercase dbt:Cite_journal dbt:Short_description
dbo:thumbnail
n4:Mir-150_SS.png?width=300
dbp:so
1244
dbp:omim
610566
dbp:altsymbols
MIR150
dbp:caption
Conserved secondary structure of miR-150 microRNA precursor
dbp:symbol
miR-150
dbo:abstract
miR-150 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interference. miR-150 functions in hematopoiesis; it regulates genes whose downstream products encourage differentiating stem cells towards becoming megakaryocytes rather than erythrocytes. It is also thought to control B and T cell differentiation, alongside mir-155.
dbp:arm
q
dbp:band
13.33
dbp:chromosome
19
dbp:entrezgene
406942
dbp:go
35195
dbp:hgncid
31537
dbp:mirbase
MI0000479
dbp:mirbaseFamily
MIPF0000197
dbp:refseq
NR_029703
dbp:rfam
RF00767
dbp:rnaType
miRNA
gold:hypernym
dbr:Family
prov:wasDerivedFrom
wikipedia-en:MiR-150?oldid=1083114975&ns=0
dbo:wikiPageLength
6068
foaf:isPrimaryTopicOf
wikipedia-en:MiR-150
Subject Item
dbr:Multiple_sclerosis_biomarkers
dbo:wikiPageWikiLink
dbr:MiR-150
Subject Item
dbr:Mir150
dbo:wikiPageWikiLink
dbr:MiR-150
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dbr:MiR-150
Subject Item
wikipedia-en:MiR-150
foaf:primaryTopic
dbr:MiR-150