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Statements

Subject Item
dbr:Interleukin
dbo:wikiPageWikiLink
dbr:Interleukin_28
Subject Item
dbr:Interleukin_28
rdf:type
yago:Part113809207 yago:Molecule114682133 wikidata:Q206229 dbo:Protein owl:Thing yago:Relation100031921 yago:Chemical114806838 yago:Abstraction100002137 yago:Matter100020827 umbel-rc:ProteinMolecule yago:Macromolecule114944888 dbo:Biomolecule yago:OrganicCompound114727670 wikidata:Q8054 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Compound114818238 yago:Unit109465459 yago:Material114580897 yago:Substance100019613 yago:Thing100002452
rdfs:label
Interleukin 28 Interleukina 28
rdfs:comment
Interleukina 28, IL-28 – wraz z interleukiną 29 zaliczana do grupy interferonów lambda. U człowieka wytwarzane są dwa rodzaje tej interleukiny (IL-29A oraz IL-29B), o zbliżonej budowie ale kodowane przez dwa oddzielne geny. Większość właściwości jest zbliżonych do interferonów lambda, jednak jej aktywność jest znacznie mniejsza. Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an "antiviral state" by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G (Interferon Stimulated Gene Factor 3). IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29. Their classification as Interferons is due to their ability to induce an antiviral state, while their additional classification as cytokines is due to their chromosomal location as well as the fact that they are encoded by multiple exons, as opposed to a single exon, as most type-I IFNs are.
foaf:name
Interleukin 28A Interleukin 28B
dbp:name
Interleukin 28A Interleukin 28B
dcterms:subject
dbc:Interleukins
dbo:wikiPageID
7816977
dbo:wikiPageRevisionID
1104391604
dbo:wikiPageWikiLink
dbr:Ribavirin dbr:ISGF3G dbr:Cytokine dbr:Genome-wide_association_study dbr:OAS1 dbr:Virus dbr:Interferon dbr:Isoform dbc:Interleukins dbr:Gene dbr:Chromosome_19 dbr:Hepatitis_C dbr:Amino_acid dbr:Interleukin_29 dbr:Type_III_interferon
owl:sameAs
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dbt:Reflist dbt:Interleukins dbt:Infobox_protein dbt:Interleukin_receptor_modulators
dbp:omim
607401 607402
dbp:altsymbols
IFNL2 IFNL3
dbp:symbol
IL28A IL28B
dbp:uniprot
Q8IZI9 Q8IZJ0
dbo:abstract
Interleukina 28, IL-28 – wraz z interleukiną 29 zaliczana do grupy interferonów lambda. U człowieka wytwarzane są dwa rodzaje tej interleukiny (IL-29A oraz IL-29B), o zbliżonej budowie ale kodowane przez dwa oddzielne geny. Większość właściwości jest zbliżonych do interferonów lambda, jednak jej aktywność jest znacznie mniejsza. Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an "antiviral state" by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G (Interferon Stimulated Gene Factor 3). IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29. Their classification as Interferons is due to their ability to induce an antiviral state, while their additional classification as cytokines is due to their chromosomal location as well as the fact that they are encoded by multiple exons, as opposed to a single exon, as most type-I IFNs are.
dbp:arm
q
dbp:band
13.13
dbp:chromosome
19
dbp:entrezgene
282616 282617
dbp:hgncid
18364 18365
dbp:refseq
NM_172139 NM_172138
gold:hypernym
dbr:Cytokine
dbo:arm
q
dbo:band
13.13
dbo:chromosome
19
dbo:entrezgene
282617 282616
dbo:hgncid
18365 18364
dbo:refseq
NM_172139 NM_172138
dbo:uniprot
Q8IZI9 Q8IZJ0
prov:wasDerivedFrom
wikipedia-en:Interleukin_28?oldid=1104391604&ns=0
dbo:wikiPageLength
6837
dbo:omim
607401 607402
dbo:symbol
IFNL2 IL28A IL28B IFNL3
foaf:isPrimaryTopicOf
wikipedia-en:Interleukin_28
Subject Item
dbr:Murine_respirovirus
dbo:wikiPageWikiLink
dbr:Interleukin_28
Subject Item
dbr:Type_II_cytokine_receptor
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dbr:Interleukin_28
Subject Item
dbr:IL-28
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dbr:Interleukin_28
Subject Item
dbr:IL-10_family
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dbr:Interleukin_28
Subject Item
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dbr:Interleukin_28
Subject Item
dbr:Interleukin-28
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dbr:Interleukin_28
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dbr:Interleukin_28
Subject Item
wikipedia-en:Interleukin_28
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dbr:Interleukin_28