| dbo:abstract
|
- Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an "antiviral state" by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G (Interferon Stimulated Gene Factor 3). IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29. Their classification as Interferons is due to their ability to induce an antiviral state, while their additional classification as cytokines is due to their chromosomal location as well as the fact that they are encoded by multiple exons, as opposed to a single exon, as most type-I IFNs are. (en)
- Interleukina 28, IL-28 – wraz z interleukiną 29 zaliczana do grupy interferonów lambda. U człowieka wytwarzane są dwa rodzaje tej interleukiny (IL-29A oraz IL-29B), o zbliżonej budowie ale kodowane przez dwa oddzielne geny. Większość właściwości jest zbliżonych do interferonów lambda, jednak jej aktywność jest znacznie mniejsza. (pl)
|
| dbo:arm
| |
| dbo:band
| |
| dbo:chromosome
| |
| dbo:entrezgene
| |
| dbo:hgncid
| |
| dbo:omim
|
- 607401 (xsd:integer)
- 607402 (xsd:integer)
|
| dbo:refseq
| |
| dbo:symbol
| |
| dbo:uniprot
| |
| dbo:wikiPageID
| |
| dbo:wikiPageLength
|
- 6837 (xsd:nonNegativeInteger)
|
| dbo:wikiPageRevisionID
| |
| dbo:wikiPageWikiLink
| |
| dbp:altsymbols
| |
| dbp:arm
| |
| dbp:band
| |
| dbp:chromosome
| |
| dbp:entrezgene
|
- 282616 (xsd:integer)
- 282617 (xsd:integer)
|
| dbp:hgncid
|
- 18364 (xsd:integer)
- 18365 (xsd:integer)
|
| dbp:name
|
- Interleukin 28A (en)
- Interleukin 28B (en)
|
| dbp:omim
|
- 607401 (xsd:integer)
- 607402 (xsd:integer)
|
| dbp:refseq
|
- NM_172138 (en)
- NM_172139 (en)
|
| dbp:symbol
| |
| dbp:uniprot
| |
| dbp:wikiPageUsesTemplate
| |
| dcterms:subject
| |
| gold:hypernym
| |
| rdf:type
| |
| rdfs:comment
|
- Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an "antiviral state" by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G (Interferon Stimulated Gene Factor 3). IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29. Their classification as Interferons is due to their ability to induce an antiviral state, while their additional classification as cytokines is due to their chromosomal location as well as the fact that they are encoded by multiple exons, as opposed to a single exon, as most type-I IFNs are. (en)
- Interleukina 28, IL-28 – wraz z interleukiną 29 zaliczana do grupy interferonów lambda. U człowieka wytwarzane są dwa rodzaje tej interleukiny (IL-29A oraz IL-29B), o zbliżonej budowie ale kodowane przez dwa oddzielne geny. Większość właściwości jest zbliżonych do interferonów lambda, jednak jej aktywność jest znacznie mniejsza. (pl)
|
| rdfs:label
|
- Interleukin 28 (en)
- Interleukina 28 (pl)
|
| owl:sameAs
| |
| prov:wasDerivedFrom
| |
| foaf:isPrimaryTopicOf
| |
| foaf:name
|
- Interleukin 28A (en)
- Interleukin 28B (en)
|
| is dbo:wikiPageRedirects
of | |
| is dbo:wikiPageWikiLink
of | |
| is foaf:primaryTopic
of | |
