About: UR-AK49

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

UR-AK49 is a drug used in scientific research which acts as a potent antagonist for the Neuropeptide Y / Pancreatic polypeptide receptor Y4, and also as a partial agonist at the histamine receptors H1 and H2. UR-AK49 is a pure antagonist at Y4 with no partial agonist effects, and although it is only slightly selective for Y4 over the related Y1 and Y5 receptors, as the first non-peptide Y4 antagonist developed UR-AK49 is expected to be useful in the study of this receptor and its role in the body.

Property	Value
dbo:abstract	UR-AK49 is a drug used in scientific research which acts as a potent antagonist for the Neuropeptide Y / Pancreatic polypeptide receptor Y4, and also as a partial agonist at the histamine receptors H1 and H2. UR-AK49 is a pure antagonist at Y4 with no partial agonist effects, and although it is only slightly selective for Y4 over the related Y1 and Y5 receptors, as the first non-peptide Y4 antagonist developed UR-AK49 is expected to be useful in the study of this receptor and its role in the body. (en)
dbo:casNumber	902154-32-9
dbo:chEMBL	486974
dbo:fdaUniiCode	5HML8P3QAT
dbo:pubchem	25149433
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dbp:c	16 (xsd:integer)
dbp:casNumber	902154 (xsd:integer)
dbp:chembl	486974 (xsd:integer)
dbp:chemspiderid	21486130 (xsd:integer)
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dbp:pubchem	25149433 (xsd:integer)
dbp:smiles	c1cCCCNCNCCCC2CCCCC2 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	QBGKYFYOFBXHFM-UHFFFAOYSA-N (en)
dbp:synonyms	UR-AK49 (en)
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dbp:watchedfields	changed (en)
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dcterms:subject	dbc:Acylguanidines dbc:Cyclohexyl_compounds dbc:Imidazoles dbc:Histamine_agonists dbc:Neuropeptide_Y_antagonists
gold:hypernym	dbr:Drug
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rdfs:comment	UR-AK49 is a drug used in scientific research which acts as a potent antagonist for the Neuropeptide Y / Pancreatic polypeptide receptor Y4, and also as a partial agonist at the histamine receptors H1 and H2. UR-AK49 is a pure antagonist at Y4 with no partial agonist effects, and although it is only slightly selective for Y4 over the related Y1 and Y5 receptors, as the first non-peptide Y4 antagonist developed UR-AK49 is expected to be useful in the study of this receptor and its role in the body. (en)
rdfs:label	UR-AK49 (en)
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foaf:depiction	wiki-commons:Special:FilePath/UR-AK49.svg
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