About: U-69,593

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

U-69,593 is a drug which acts as a potent and selective κ1-opioid receptor agonist. In animal studies it has been shown to produce antinociception, anti-inflammation, anxiolysis (at low doses), respiratory depression, and diuresis, while having little effect on gastrointestinal motility. It also inhibits the peripheral, though not central secretion of oxytocin and vasopressin in rats.

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dbo:abstract
  • U-69,593 is a drug which acts as a potent and selective κ1-opioid receptor agonist. In animal studies it has been shown to produce antinociception, anti-inflammation, anxiolysis (at low doses), respiratory depression, and diuresis, while having little effect on gastrointestinal motility. It also inhibits the peripheral, though not central secretion of oxytocin and vasopressin in rats. (en)
dbo:casNumber
  • 96744-75-1
dbo:chEBI
  • 73357
dbo:chEMBL
  • 440765
dbo:fdaUniiCode
  • J5S4K6TKTG
dbo:pubchem
  • 105104
dbo:thumbnail
dbo:wikiPageID
  • 26985762 (xsd:integer)
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  • 6557 (xsd:nonNegativeInteger)
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  • 1081875656 (xsd:integer)
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  • none (en)
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  • 22 (xsd:integer)
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  • 96744 (xsd:integer)
dbp:chebi
  • 73357 (xsd:integer)
dbp:chembl
  • 440765 (xsd:integer)
dbp:chemspiderid
  • 94828 (xsd:integer)
dbp:h
  • 32 (xsd:integer)
dbp:iupacName
  • N-methyl-2-phenyl-N-[-7--1-oxaspiro[4.5]dec-8-yl]acetamide (en)
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  • 1655 (xsd:integer)
dbp:n
  • 2 (xsd:integer)
dbp:o
  • 2 (xsd:integer)
dbp:pubchem
  • 105104 (xsd:integer)
dbp:smiles
  • O=CCc4ccccc4 (en)
dbp:unii
  • J5S4K6TKTG (en)
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rdfs:comment
  • U-69,593 is a drug which acts as a potent and selective κ1-opioid receptor agonist. In animal studies it has been shown to produce antinociception, anti-inflammation, anxiolysis (at low doses), respiratory depression, and diuresis, while having little effect on gastrointestinal motility. It also inhibits the peripheral, though not central secretion of oxytocin and vasopressin in rats. (en)
rdfs:label
  • U-69,593 (en)
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