About: Type XVIII collagen

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Type XVIII collagen is a type of collagen which can be cleaved to form endostatin. The endostatin is from the c terminus end of the collagen XVIII, and is known to have an inhibitory effect on the growth of blood vessels. This is seen with tumors, where endostatin inhibits the growth of the blood vessels of the tumor as well as the overall growth of the tumor.

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dbo:abstract
  • El col·lagen tipus XVIII és un tipus de col·lagen que es pot hidrolitzar per a formar . (ca)
  • Type XVIII collagen is a type of collagen which can be cleaved to form endostatin. The endostatin is from the c terminus end of the collagen XVIII, and is known to have an inhibitory effect on the growth of blood vessels. This is seen with tumors, where endostatin inhibits the growth of the blood vessels of the tumor as well as the overall growth of the tumor. The collagen XVIII is located within the basement membrane, and plays a major role in the integrity of the structure of the basement membrane for both endothelial and epithelial cells. The collagen XVIII has three different isoforms. While each of the isoforms has the same C-terminus end, they have a varying structure on the N-terminus end, which results in the formation of short, medium or long form Collagen XVIII. (en)
dbo:arm
  • q
dbo:band
  • 22.3
dbo:chromosome
  • 21
dbo:entrezgene
  • 80781
dbo:hgncid
  • 2195
dbo:omim
  • 120328 (xsd:integer)
dbo:refseq
  • NM_130445
dbo:symbol
  • COL18A1
dbo:uniprot
  • P39060
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dbp:arm
  • q (en)
dbp:band
  • 22.300000 (xsd:double)
dbp:chromosome
  • 21 (xsd:integer)
dbp:entrezgene
  • 80781 (xsd:integer)
dbp:hgncid
  • 2195 (xsd:integer)
dbp:name
  • collagen, type XVIII, alpha 1 (en)
dbp:omim
  • 120328 (xsd:integer)
dbp:refseq
  • NM_130445 (en)
dbp:symbol
  • COL18A1 (en)
dbp:uniprot
  • P39060 (en)
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dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • El col·lagen tipus XVIII és un tipus de col·lagen que es pot hidrolitzar per a formar . (ca)
  • Type XVIII collagen is a type of collagen which can be cleaved to form endostatin. The endostatin is from the c terminus end of the collagen XVIII, and is known to have an inhibitory effect on the growth of blood vessels. This is seen with tumors, where endostatin inhibits the growth of the blood vessels of the tumor as well as the overall growth of the tumor. (en)
rdfs:label
  • Col·lagen tipus XVIII (ca)
  • Type XVIII collagen (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
foaf:name
  • collagen, type XVIII, alpha 1 (en)
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