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The bacterial type IV secretion system, also known as the type IV secretion system or the T4SS, is a secretion protein complex found in gram negative bacteria, gram positive bacteria, and archaea. It is able to transport proteins and DNA across the cell membrane. The type IV secretion system is just one of many bacterial secretion systems. Type IV secretion systems are related to conjugation machinery which generally involve a single-step secretion system and the use of a pilus. Type IV secretion systems are used for conjugation, DNA exchange with the extracellular space, and for delivering proteins to target cells. The type IV secretion system is divided into type IVA and type IVB based on genetic ancestry.

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  • Le système de sécrétion de type IV (aussi connu sous le nom T4SS) est un complexe protéique de sécrétion que l’on retrouve souvent chez les bactéries. Il s’agit d’un moyen pour permettre le transport de protéines ou d’ADN à travers la membrane cellulaire. Le T4SS est un système utilisé pour la conjugaison bactérienne, pour l’échange de matériel génétique (par exemple de l’ADN plasmidique) avec le milieu extra-cellulaire et pour délivrer des protéines dans des cellules cibles. Les systèmes de sécrétion de type IV (SST4) sont divisés en quatre familles : IVA (regroupant les SST4-F et -P), IVB, IVGI et IVGP. Le T4SS intervient par exemple pour l’insertion du plasmide dans les plantes avec Agrobacterium tumefaciens, la délivrance de toxine chez Bordetella pertussis et Legionella pneumophila ou encore avec le pilus sexuel F. (fr)
  • The bacterial type IV secretion system, also known as the type IV secretion system or the T4SS, is a secretion protein complex found in gram negative bacteria, gram positive bacteria, and archaea. It is able to transport proteins and DNA across the cell membrane. The type IV secretion system is just one of many bacterial secretion systems. Type IV secretion systems are related to conjugation machinery which generally involve a single-step secretion system and the use of a pilus. Type IV secretion systems are used for conjugation, DNA exchange with the extracellular space, and for delivering proteins to target cells. The type IV secretion system is divided into type IVA and type IVB based on genetic ancestry. Notable instances of the type IV secretion system include the plasmid insertion into plants of Agrobacterium tumefaciens, the toxin delivery methods of Bordetella pertussis (whooping cough) and Legionella pneumophila (Legionnaires' disease), and the F sex pilus. (en)
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  • The bacterial type IV secretion system, also known as the type IV secretion system or the T4SS, is a secretion protein complex found in gram negative bacteria, gram positive bacteria, and archaea. It is able to transport proteins and DNA across the cell membrane. The type IV secretion system is just one of many bacterial secretion systems. Type IV secretion systems are related to conjugation machinery which generally involve a single-step secretion system and the use of a pilus. Type IV secretion systems are used for conjugation, DNA exchange with the extracellular space, and for delivering proteins to target cells. The type IV secretion system is divided into type IVA and type IVB based on genetic ancestry. (en)
  • Le système de sécrétion de type IV (aussi connu sous le nom T4SS) est un complexe protéique de sécrétion que l’on retrouve souvent chez les bactéries. Il s’agit d’un moyen pour permettre le transport de protéines ou d’ADN à travers la membrane cellulaire. Le T4SS est un système utilisé pour la conjugaison bactérienne, pour l’échange de matériel génétique (par exemple de l’ADN plasmidique) avec le milieu extra-cellulaire et pour délivrer des protéines dans des cellules cibles. (fr)
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  • Système de sécrétion de type IV (fr)
  • Type IV secretion system (en)
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