About: Trifarotene

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Trifarotene, sold under the brand name Aklief, is a medication for the topical treatment of acne vulgaris. It is a retinoid; more specifically, it is a fourth generation selective retinoic acid receptor (RAR)-γ agonist. Trifarotene was granted orphan drug designation for the treatment of congenital ichthyosis by both the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA). It was approved for medical use in the United States in October 2019. In December 2019, its labelling and package leaflet text received a decentralised approval for 16 European countries.

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dbo:abstract
  • Trifaroten ist ein Retinoid der vierten Generation und wurde im Oktober 2019 in des USA unter dem Namen Aklief zur lokalen Behandlung der Akne vulgaris zugelassen. (de)
  • Trifarotene, sold under the brand name Aklief, is a medication for the topical treatment of acne vulgaris. It is a retinoid; more specifically, it is a fourth generation selective retinoic acid receptor (RAR)-γ agonist. Trifarotene was granted orphan drug designation for the treatment of congenital ichthyosis by both the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA). It was approved for medical use in the United States in October 2019. In December 2019, its labelling and package leaflet text received a decentralised approval for 16 European countries. (en)
  • Трифаротен — ретиноид четвёртого поколения, применяемый для лечения акне. Одобрен для применения в США с 2019 года. (ru)
dbo:alternativeName
  • Aklief (en)
dbo:casNumber
  • 895542-09-3
dbo:chEMBL
  • 3707313
dbo:drugbank
  • DB12808
dbo:fdaUniiCode
  • 0J8RN2W0HK
dbo:kegg
  • D11225
dbo:medlinePlus
  • a620004
dbo:pubchem
  • 11518241
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  • D10 (en)
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  • AD06 (en)
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dbp:chemspiderid
  • 9693029 (xsd:integer)
dbp:class
  • Skin and mucous membrane agents (en)
dbp:dailymedid
  • Trifarotene (en)
dbp:drugbank
  • DB12808 (en)
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  • 33 (xsd:integer)
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dbp:kegg
  • D11225 (en)
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  • Rx-only (en)
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  • Rx-only (en)
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  • Rx-only (en)
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  • a620004 (en)
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dbp:pregnancyAu
  • D (en)
dbp:pregnancyCategory
  • Contraindicated (en)
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  • 11518241 (xsd:integer)
dbp:routesOfAdministration
dbp:smiles
  • CCc1ccccc1N1CCCC1 (en)
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  • 1 (xsd:integer)
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  • MFBCDACCJCDGBA-UHFFFAOYSA-N (en)
dbp:synonyms
  • CD5789 (en)
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  • Aklief (en)
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  • Trifaroten ist ein Retinoid der vierten Generation und wurde im Oktober 2019 in des USA unter dem Namen Aklief zur lokalen Behandlung der Akne vulgaris zugelassen. (de)
  • Trifarotene, sold under the brand name Aklief, is a medication for the topical treatment of acne vulgaris. It is a retinoid; more specifically, it is a fourth generation selective retinoic acid receptor (RAR)-γ agonist. Trifarotene was granted orphan drug designation for the treatment of congenital ichthyosis by both the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA). It was approved for medical use in the United States in October 2019. In December 2019, its labelling and package leaflet text received a decentralised approval for 16 European countries. (en)
  • Трифаротен — ретиноид четвёртого поколения, применяемый для лечения акне. Одобрен для применения в США с 2019 года. (ru)
rdfs:label
  • Trifaroten (de)
  • Трифаротен (ru)
  • Trifarotene (en)
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