About: Tesofensine

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Tesofensine (NS2330) is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs, which is being developed for the treatment of obesity. Tesofensine was originally developed by a Danish biotechnology company, NeuroSearch, who transferred the rights to Saniona in 2014. As of 2019, tesofensine has been discontinued for the treatment of Alzheimer's and Parkinson's disease but is in phase III clinical trial for obesity.

Property Value
dbo:abstract
  • La tésofensine (NS2330) est un inhibiteur de la sérotonine, de la noradrénaline et de la dopamine de la famille pharmaceutique des phényltropanes, qui est actuellement développé pour le traitement symptomatique de l’obésité par la société Exiol.La tésofensine a, à l’origine, été étudiée par une compagnie danoise de biotechnologie, Neurosearch, qui a transféré ses droits à Saniona en 2014. Depuis 2019, la tésofensine a été dissociée des traitements contre les maladies d'Alzheimer et de Parkinson au profit d’essais cliniques en phase III pour le traitement de l’obésité. (fr)
  • Tesofensine (NS2330) is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs, which is being developed for the treatment of obesity. Tesofensine was originally developed by a Danish biotechnology company, NeuroSearch, who transferred the rights to Saniona in 2014. As of 2019, tesofensine has been discontinued for the treatment of Alzheimer's and Parkinson's disease but is in phase III clinical trial for obesity. (en)
  • Tesofensina é um inibidor de recaptação de serotonina-noradrenalina-dopamina (SNDRI) da classe das fenetilaminas utilizado pela medicina no tratamento da Doença de Parkinson e Alzheimer. Ainda, estudos feitos na Dinamarca, por cientistas da Universidade de Copenhague em 2008 mostraram eficácia no tratamento da obesidade. (pt)
dbo:bioavailability
  • 90.000000 (xsd:float)
dbo:casNumber
  • 195875-84-4
dbo:fdaUniiCode
  • BLH9UKX9V1
dbo:pubchem
  • 11370864
dbo:thumbnail
dbo:wikiPageID
  • 13152996 (xsd:integer)
dbo:wikiPageLength
  • 15187 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1085263801 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • None (en)
dbp:bioavailability
  • 90.0
dbp:c
  • 17 (xsd:integer)
dbp:casNumber
  • 195875 (xsd:integer)
dbp:chemspiderid
  • 9545781 (xsd:integer)
dbp:cl
  • 2 (xsd:integer)
dbp:eliminationHalfLife
  • 792000.0
dbp:excretion
  • Not applicable (en)
dbp:h
  • 23 (xsd:integer)
dbp:iupacName
  • -3 (xsd:integer)
dbp:legalUs
  • Investigational New Drug (en)
dbp:metabolism
  • 15 (xsd:integer)
dbp:n
  • 1 (xsd:integer)
dbp:o
  • 1 (xsd:integer)
dbp:pregnancyCategory
  • Not applicable (en)
dbp:pubchem
  • 11370864 (xsd:integer)
dbp:routesOfAdministration
  • Oral (en)
dbp:smiles
  • Clc1ccc[C@H]3C[C@H]2N[C@H][C@@H]3COCC (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • VCVWXKKWDOJNIT-ZOMKSWQUSA-N (en)
dbp:unii
  • BLH9UKX9V1 (en)
dbp:verifiedfields
  • changed (en)
dbp:verifiedrevid
  • 470603052 (xsd:integer)
dbp:watchedfields
  • changed (en)
dbp:width
  • 170 (xsd:integer)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • La tésofensine (NS2330) est un inhibiteur de la sérotonine, de la noradrénaline et de la dopamine de la famille pharmaceutique des phényltropanes, qui est actuellement développé pour le traitement symptomatique de l’obésité par la société Exiol.La tésofensine a, à l’origine, été étudiée par une compagnie danoise de biotechnologie, Neurosearch, qui a transféré ses droits à Saniona en 2014. Depuis 2019, la tésofensine a été dissociée des traitements contre les maladies d'Alzheimer et de Parkinson au profit d’essais cliniques en phase III pour le traitement de l’obésité. (fr)
  • Tesofensine (NS2330) is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs, which is being developed for the treatment of obesity. Tesofensine was originally developed by a Danish biotechnology company, NeuroSearch, who transferred the rights to Saniona in 2014. As of 2019, tesofensine has been discontinued for the treatment of Alzheimer's and Parkinson's disease but is in phase III clinical trial for obesity. (en)
  • Tesofensina é um inibidor de recaptação de serotonina-noradrenalina-dopamina (SNDRI) da classe das fenetilaminas utilizado pela medicina no tratamento da Doença de Parkinson e Alzheimer. Ainda, estudos feitos na Dinamarca, por cientistas da Universidade de Copenhague em 2008 mostraram eficácia no tratamento da obesidade. (pt)
rdfs:label
  • Tésofensine (fr)
  • Tesofensine (en)
  • Tesofensina (pt)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
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