About: Tampramine

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Tampramine (AHR-9,377) is a tricyclic antidepressant (TCA) which was developed in the 1980s but was never marketed. Despite being a TCA, it acts as a selective norepinephrine reuptake inhibitor and has negligible affinity for adrenergic, histaminergic, and muscarinic receptors. It was found to be effective in the forced swim test (FST) model of depression in animal studies but is not known to have ever been trialed in humans.

Property	Value
dbo:abstract	Tampramine (AHR-9,377) is a tricyclic antidepressant (TCA) which was developed in the 1980s but was never marketed. Despite being a TCA, it acts as a selective norepinephrine reuptake inhibitor and has negligible affinity for adrenergic, histaminergic, and muscarinic receptors. It was found to be effective in the forced swim test (FST) model of depression in animal studies but is not known to have ever been trialed in humans. (en)
dbo:casNumber	(fumarate) 83166-17-0
dbo:fdaUniiCode	47GSE5RM8N
dbo:pubchem	54961
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dbp:c	23 (xsd:integer)
dbp:casNumber	83166 (xsd:integer)
dbp:chemspiderid	49631 (xsd:integer)
dbp:h	24 (xsd:integer)
dbp:iupacName	N,N-Dimethyl-3-propan-1-amine (en)
dbp:legalStatus	Uncontrolled (en)
dbp:n	4 (xsd:integer)
dbp:pubchem	54961 (xsd:integer)
dbp:routesOfAdministration	Oral (en)
dbp:smiles	CNCCCN1c2ccccc2Cc4ccccc4 (en)
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gold:hypernym	dbr:Antidepressant
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rdfs:comment	Tampramine (AHR-9,377) is a tricyclic antidepressant (TCA) which was developed in the 1980s but was never marketed. Despite being a TCA, it acts as a selective norepinephrine reuptake inhibitor and has negligible affinity for adrenergic, histaminergic, and muscarinic receptors. It was found to be effective in the forced swim test (FST) model of depression in animal studies but is not known to have ever been trialed in humans. (en)
rdfs:label	Tampramine (en)
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