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In enzymology, a tRNA (uracil-5-)-methyltransferase (EC 2.1.1.35) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + tRNA containing uridine at position 54 S-adenosyl-L-homocysteine + tRNA containing ribothymidine at position 54 Thus, the two substrates of this enzyme are S-adenosyl methionine and tRNA containing uridine at position 54, whereas its two products are S-adenosylhomocysteine and tRNA containing ribothymidine at position 54.

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  • In enzymology, a tRNA (uracil-5-)-methyltransferase (EC 2.1.1.35) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + tRNA containing uridine at position 54 S-adenosyl-L-homocysteine + tRNA containing ribothymidine at position 54 Thus, the two substrates of this enzyme are S-adenosyl methionine and tRNA containing uridine at position 54, whereas its two products are S-adenosylhomocysteine and tRNA containing ribothymidine at position 54. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase. Other names in common use include ribothymidyl synthase, transfer RNA uracil 5-methyltransferase, transfer RNA uracil methylase, tRNA uracil 5-methyltransferase, m5U-methyltransferase, tRNA:m5U54-methyltransferase, and RUMT. (en)
  • La tRNA (uracile-5-)-metiltransferasi è un enzima appartenente alla classe delle transferasi, che catalizza la seguente reazione: S-adenosil-L-metionina + tRNA contenente uridina in posizione 54 ⇄ S-adenosil-L-omocisteina + tRNA contenente ribotimidina in posizione 54 Fino al 25% delle basi di un tRNA maturo sono ipermodificate o ipomodificate. Una modificazione quasi universale è la conversione di U54 (nel TΨC loop) in ribotimidina. Tale modificazione è presente nella maggior parte delle specie note. A differenza di questo enzima, la metilenetetraidrofolato—tRNA-(uracile-5-)-metiltransferasi (ossida il FADH2). numero EC 2.1.1.74, utilizza il 5,10-metilenetetraidrofolato ed il FADH2 per fornire gli atomi necessari alla metilazione di U54. (it)
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  • 2.1.1.35
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  • 14025727 (xsd:integer)
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  • 3748 (xsd:nonNegativeInteger)
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  • 976280411 (xsd:integer)
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  • 37257 (xsd:integer)
dbp:ecNumber
  • 2.100000 (xsd:double)
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  • 9021 (xsd:integer)
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  • 2 (xsd:integer)
dbp:name
  • tRNA -methyltransferase (en)
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  • In enzymology, a tRNA (uracil-5-)-methyltransferase (EC 2.1.1.35) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + tRNA containing uridine at position 54 S-adenosyl-L-homocysteine + tRNA containing ribothymidine at position 54 Thus, the two substrates of this enzyme are S-adenosyl methionine and tRNA containing uridine at position 54, whereas its two products are S-adenosylhomocysteine and tRNA containing ribothymidine at position 54. (en)
  • La tRNA (uracile-5-)-metiltransferasi è un enzima appartenente alla classe delle transferasi, che catalizza la seguente reazione: S-adenosil-L-metionina + tRNA contenente uridina in posizione 54 ⇄ S-adenosil-L-omocisteina + tRNA contenente ribotimidina in posizione 54 (it)
rdfs:label
  • TRNA (uracile-5-)-metiltransferasi (it)
  • TRNA (uracil-5-)-methyltransferase (en)
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  • tRNA (uracil-5-)-methyltransferase (en)
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