About: Surotomycin

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Surotomycin was an investigational oral antibiotic. This antibiotic was under investigation by Merck & Co (who acquired Cubist Pharmaceuticals) for the treatment of life-threatening Diarrhea, commonly caused by the bacterium Clostridium difficile. After reaching phase III in clinical trials, its production was discontinued in 2017 due to its non-superiority to current therapies.

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  • Surotomycin was an investigational oral antibiotic. This antibiotic was under investigation by Merck & Co (who acquired Cubist Pharmaceuticals) for the treatment of life-threatening Diarrhea, commonly caused by the bacterium Clostridium difficile. After reaching phase III in clinical trials, its production was discontinued in 2017 due to its non-superiority to current therapies. (en)
dbo:iupacName
  • (3S)-3-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]carbamoyl}-3-[(2R)-3-carbamoyl-2-[(2R)-3-(1H-indol-3-yl)-2-[(2E)-3-(4-pentylphenyl)but-2-enamido]propanamido]propanamido]propanoic acid (en)
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  • Structure_of_surotomycin.png (en)
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  • Surotomycin was an investigational oral antibiotic. This antibiotic was under investigation by Merck & Co (who acquired Cubist Pharmaceuticals) for the treatment of life-threatening Diarrhea, commonly caused by the bacterium Clostridium difficile. After reaching phase III in clinical trials, its production was discontinued in 2017 due to its non-superiority to current therapies. (en)
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  • Surotomycin (en)
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