About: Subvalvular aortic stenosis (canine)

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Canine subvalvular aortic stenosis (SAS) is an abnormal, congenital heart murmur caused by subaortic stenosis (SAS). There is a high incidence of this condition identified in large and giant breed dogs like the Rottweiler, Newfoundland, Golden Retriever, Boxer, German Shepherd, English Bulldog, Great Dane, German Shorthaired Pointer, and Bouvier des Flandres.

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  • Canine subvalvular aortic stenosis (SAS) is an abnormal, congenital heart murmur caused by subaortic stenosis (SAS). There is a high incidence of this condition identified in large and giant breed dogs like the Rottweiler, Newfoundland, Golden Retriever, Boxer, German Shepherd, English Bulldog, Great Dane, German Shorthaired Pointer, and Bouvier des Flandres. It is a common congenital heart defect that consists of abnormal tissue located just below the aortic valve that creates an obstruction the heart has to overcome to pump blood out to the body. As a result, the heart muscle can become thickened. The blood is pumped at a higher speed and pressure across the stenosis into the aorta, creating a heart murmur. This genetic trait is polygenic. An animal might have the genes for SAS, yet have no actual sign of SAS. Also, an animal might have signs of subaortic stenosis, and yet offspring with SAS may not demonstrate clinical signs for a couple of generations. Any animal that has subaortic stenosis should not be bred because they can pass the defect on to future offspring. (en)
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  • Canine subvalvular aortic stenosis (SAS) is an abnormal, congenital heart murmur caused by subaortic stenosis (SAS). There is a high incidence of this condition identified in large and giant breed dogs like the Rottweiler, Newfoundland, Golden Retriever, Boxer, German Shepherd, English Bulldog, Great Dane, German Shorthaired Pointer, and Bouvier des Flandres. (en)
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  • Subvalvular aortic stenosis (canine) (en)
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