About: Specificity factor

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

A specificity factor is an amino acid sequence that mediates target recognition in RNA polymerase. An example is the sigma subunit of the Escherichia coli RNA polymerase holoenzyme which regulates a binding σ subunit of molecular weight 70 kDa. Under some conditions, some of the 70-kDa subunits are replaced by one of the other, more-specific factors. For instance, when bacteria are subjected to heat stress, some of the 70-kDa subunits are replaced by a 32-kDa subunit; when bound to σ32, RNA polymerase is directed to a specialized set of promoters with a different consensus sequence.

Property Value
dbo:abstract
  • A specificity factor is an amino acid sequence that mediates target recognition in RNA polymerase. An example is the sigma subunit of the Escherichia coli RNA polymerase holoenzyme which regulates a binding σ subunit of molecular weight 70 kDa. Under some conditions, some of the 70-kDa subunits are replaced by one of the other, more-specific factors. For instance, when bacteria are subjected to heat stress, some of the 70-kDa subunits are replaced by a 32-kDa subunit; when bound to σ32, RNA polymerase is directed to a specialized set of promoters with a different consensus sequence. (en)
dbo:wikiPageID
  • 619275 (xsd:integer)
dbo:wikiPageLength
  • 1161 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1118739343 (xsd:integer)
dbo:wikiPageWikiLink
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:comment
  • A specificity factor is an amino acid sequence that mediates target recognition in RNA polymerase. An example is the sigma subunit of the Escherichia coli RNA polymerase holoenzyme which regulates a binding σ subunit of molecular weight 70 kDa. Under some conditions, some of the 70-kDa subunits are replaced by one of the other, more-specific factors. For instance, when bacteria are subjected to heat stress, some of the 70-kDa subunits are replaced by a 32-kDa subunit; when bound to σ32, RNA polymerase is directed to a specialized set of promoters with a different consensus sequence. (en)
rdfs:label
  • Specificity factor (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License